kv1.3-in-1 — TargetMol Chemicals

Search Result

Search Results for " kv1.3-in-1 "

Compounds

Cat No.	Product Name	Synonyms	Targets
T79445	KV1.3-IN-1		Potassium Channel
	KV1.3-IN-1 (Compound trans-18), a selective KV1.3 channel inhibitor with IC50 values of 230 nM in Ltk cells and 26.12 nM in PHA-activated T-lymphocytes, disrupts intracellular Ca2+ signaling and impedes T-cell activation...		Potassium Channel
T80497	KTX-Sp2		Potassium Channel
	KTX-Sp2, a potassium channel toxin, effectively blocks exogenous voltage-gated potassium channels Kv1.1, Kv1.2, and Kv1.3, as well inhibits the endogenous Kv1.3 channel and suppresses Ca2+ signaling in Jurkat T cells. Ad...		Potassium Channel
T80050	Noxiustoxin		Potassium Channel
	Noxiustoxin, a toxin extracted from the venom of the Mexican scorpion Centruroides noxius, inhibits both the voltage-dependent potassium channel (Kv1.3, IC50 = 360 nM) and the calcium-activated potassium channel. It is s...		Potassium Channel
T76280	Dalazatide
	Dalazatide (ShK-186) is a specific inhibitor of the Kv1.3 potassium channel, employed in researching autoimmune conditions including multiple sclerosis (MS), lupus erythematosus, psoriasis, rheumatoid arthritis, type 1 d...
T76280L	Dalazatide TFA
	Dalazatide (ShK-186) TFA, a precise Kv1.3 potassium channel peptide inhibitor, is employed in researching autoimmune conditions, including multiple sclerosis (MS), lupus erythematosus, psoriasis, rheumatoid arthritis, ty...
T80436	Hemitoxin		Potassium Channel
	Hemitoxin, a scorpion-venom peptide, functions as a K+ channel blocker and selectively inhibits rat Kv1.1, Kv1.2, and Kv1.3 channels expressed in Xenopus oocytes, with respective IC50 values of 13 nM, 16 nM, and 2 nM [1]...		Potassium Channel
T80174	BmP02		Potassium Channel
	BmP02, a compound isolated from Chinese scorpion (Buthus martensi Karsch) venom, acts as a selective Kv1.3 channel blocker and a highly-selective Kv4.2 modulator. It delays Kv4.2 inactivation in HEK293T cells, exhibiting...		Potassium Channel
T80528	Ssm spooky toxin	SsTx Toxin	Potassium Channel
	Ssm Spooky Toxin, derived from Scolopendra mutilans, exhibits potent lethality affecting both hematological and respiratory systems primarily through the inhibition of KCNQ (voltage-gated potassium channel family 7) chan...		Potassium Channel
T80187	HsTX1		Potassium Channel
	HsTX1, a 34-residue, C-terminally amidated peptide isolated from the scorpion Heterometrus spinnifer, features four disulfide bridges and acts as a potassium channel inhibitor. It exhibits an IC50 of 12 pM for Kv1.3, imp...		Potassium Channel
T80066	ShK toxin		Potassium Channel
	ShK toxin, isolated from the Caribbean sea anemone (Stichodactyla helianthus), is an inhibitor of the voltage-dependent potassium channel (Kv1.3 channel). It competes with dendrotoxin I and α-dendrotoxin in binding to ra...		Potassium Channel
T80483	Aam-KTX		Potassium Channel
	Aam-KTX, a toxic peptide sourced from Mesobuthus eupeus scorpion venom, acts as a selective K_v channel inhibitor, exhibiting IC_50 values of 1.1 nM for K_v1.3 channels and >750 nM for K_v1.1 channels. This compound show...		Potassium Channel
T35426	β-Defensin-1 (human) (trifluoroacetate salt)
	β-Defensin-1 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth ofB. adolescentis,L. acidophilus...
T21819	Psora 4
	Psora-4 is a potent and selective inhibitor of K v 1.3 (voltage-gated potassium channels) with a Hill coefficient of 2 and an EC50 value of 3 nM [1]. Psora-4 has immunosuppressive activity and inhibits proliferation of h...