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Search Results for " jak-in-11 "

3

Compounds

Cat No. Product Name Synonyms Targets
T12549 JAK-IN-11 R-348 JAK
JAK-IN-11 (R-348) is a potent and selective inhibitor of JAK, has the potential for the skin disorders treatment.
T9811 JAK3-IN-11
JAK3-IN-11 (Compound 12) exhibits potent, noncytotoxic, irreversible, orally active JAK3 inhibitory activity (IC50 = 1.7 nM) with an excellent selectivity profile (>588-fold compared to other JAK isoforms), covalently bi...
T1849 Momelotinib CYT11387,CYT387,LM-1149 Apoptosis , JAK , Autophagy
Momelotinib (LM-1149) is an orally bioavailable small-molecule inhibitor of Janus kinases 1 and 2 (JAK1/2) with IC50 of 11 nM/18 nM. JAK1/2 inhibitor CYT387 competes with JAK1/2 for ATP binding, which may result in inhib...
TargetMol