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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9564 | IRE1α kinase-IN-1 | IRE1 | |
IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM. It displays 100-fold selectivity for IRE1α over the IRE1β isoform. It inhibits ER stress-induced IRE1α oligomerization and autophosph... | |||
T38841 | IRE1α kinase-IN-2 | IRE1α kinase-IN-2 | |
IRE1α kinase-IN-2 is a highly potent inhibitor of IRE1α kinase, demonstrating an EC50 of 0.82 μM. It effectively impedes IRE1α kinase autophosphorylation with an IC50 of 3.12 μM. Additionally, IRE1α kinase-IN-2 effective... | |||
T40336 | IRE1α kinase-IN-6 | IRE1α kinase-IN-6 | |
IRE1α kinase-IN-6 is a potent IRE1α inhibitor with an IC 50 value of 4.4 nM. | |||
T9848 | GSK2850163 (S enantiomer) | IRE1 | |
GSK2850163 (S enantiomer) is the inactive enantiomer of GSK2850163. GSK2850163 is an novel inhibitor of inositol-requiring enzyme-1 alpha (IRE1a). |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04753 | IRE1 Protein, Human, Recombinant (aa 465-977) | Human | Baculovirus-Insect Cells |
Endoplasmic reticulum stress and hypoxia are necessary components of malignant tumors growth and suppression of ERN1 (from endoplasmic reticulum to nuclei-1) signalling pathway, which is linked to the apoptosis and cell ... | |||
TMPY-04413 | IRE1 Protein, Human, Recombinant (aa 465-977, His & GST) | Human | Baculovirus-Insect Cells |
Endoplasmic reticulum stress and hypoxia are necessary components of malignant tumors growth and suppression of ERN1 (from endoplasmic reticulum to nuclei-1) signalling pathway, which is linked to the apoptosis and cell ... |