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Search Result

Search Results for " ilei "

24

Compounds

1

Natural Products

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T61710 Antileishmanial agent-7
Antileishmanial agent-7 (compound 23) exhibits strong antileishmanial activity against Leishmania donovani and L-6, with IC50 values of 6.89 and 259 μM, respectively [1].
T61199 Antileishmanial agent-2
Antileishmanial agent-2 demonstrates potent submicromolar antileishmanial activity (IC50 = 0.29 μM) and a remarkable selectivity index against mammalian cells.
T61560 Antileishmanial agent-5
Antileishmanial agent-4 is a ribonucleoside analogue with potent activity against L.infantum and T.cruzi, having EC 50 values of 0.68 μM and 0.83 μM, respectively [1].
T63281 Antileishmanial agent-11
Antileishmanial agent-11 is a potent antileishmanial agent that acts on Leishmania brazilensis (IC50: 28.3 μM), Leishmania infantum (IC50: 24.8 μM) and T. cruzi (IC50: 13.0 μM) with outstanding antiprotozoal effect.
T78963 Antileishmanial agent-16 Parasite
Antileishmanial agent-16 (compound 14c), an anti-Leishmania agent, exhibits potent activity against Leishmania major promastigotes (IC50 = 0.59 µM) and amastigotes (IC50 = 0.81 µM), while maintaining a favorable safety p...
T61391 Antileishmanial agent-3
Antileishmanial agent-3 (Compound 13) effectively inhibits the growth of Leishmania major [1].
T62574 Antileishmanial agent-6
Antileishmanial agent-6 is a potent anti-leishmanial agent with anti-leishmanial activity (IC50: 0.54 μM) and cytotoxicity (IC50: 10.2 μM) against Leishmania donovani and L-6.
T78964 Antileishmanial agent-17 Parasite
Antileishmanial agent-17, a coumarin hybrid, exhibits potent antileishmanial activity (IC50 <0.78 μM) while proving non-toxic to normal VERO cells. It specifically interacts with the folate pathway enzymes pteridine redu...
T79449 Antileishmanial agent-19 Parasite
Compound F27 (Antileishmanial agent-19) is an antileishmanial compound effective against L. donovani promastigotes, demonstrating an IC50 of 3.39 μM. It functions by inhibiting the Leishmania prolyl-tRNA synthetase and d...
T79471 Antileishmanial agent-20 Parasite
Antileishmanial agent-20 exhibits selectivity against the Leishmania parasite, with IC50 values of 2.8 μM for L. infantum and 0.2 μM for L. braziliensis. It is a potential research tool for studying these parasites [1].
T79633 Antileishmanial agent-22 Parasite
Antileishmanial agent-22 (compound 15b) serves as an antiparasitic and antibacterial, exhibiting activities against Leishmania (IC50 = 0.408 μM), malaria, and tuberculosis. It operates on an antifolate mechanism, suppres...
T60638 Antileishmanial agent-8
Antileishmanial agent-8 (compound 18) shows potent and selective activity against Leishmania donovani ( L. donovani ) (IC50 = 5.64 μM) with relatively low cytotoxicity in L-6 cells (IC 50 =73.9 μM) [1].
T61416 Antileishmanial agent-9
Antileishmanial agent-9 (compound 16c) exhibits potent and selective activity against Leishmania donovani (L. donovani) with an IC50 value of 4.01 μM. In addition, this compound demonstrates relatively low cytotoxicity i...
T62330 Antileishmanial agent-12
Antileishmanial agent-12 (compound 5a) is a potent anti-leishmanial agent with antibacterial activity against Leishmania brazilensis (IC50: 14.9 μM), Leishmania infantum (IC50: 21.3 μM) and T. cruzi (IC50. 9.3 μM). 9.3 μ...
T78680 Antileishmanial agent-14 Parasite
Antileishmanial agent-14, a sulfuretin analog, exhibits potential activity against Leishmania donovani promastigotes (IC 50 = 4.1 μM) and inhibits infection by L. donovani amastigotes (IC 50 = 11.1 μM) [1].
T78962 Antileishmanial agent-15 Parasite
Antileishmanial agent-15 (compound 13c) exhibits potent activity against L. major promastigotes and amastigotes, demonstrating IC50 values of 0.78 μM for promastigotes and 0.99 μM for amastigotes, while also showing cyto...
T61100 Antileishmanial agent-4
Antileishmanial agent-4, a ribonucleoside analogue, functions as an antileishmanial agent [1].
T79419 Antileishmanial agent-24 Parasite
Antileishmanial agent-24 (compound 33) exhibits antileishmanial activity, demonstrating an inhibitory concentration 50 (IC50) value of 5.39 μM against amastigotes [1].
T79632 Antileishmanial agent-21 Parasite
Antileishmanial agent-21 (compound 4e) functions as an inhibitor of Leishmania pteridine reductase 1 (Lm-PTR1), employing an anti-folate mechanism. Its antileishmanial effects can be negated by folic acid and leucovorin....
T79390 Antileishmanial agent-23 Parasite
Antileishmanial agent-23 (compound G1/9), a potent and selective trypanothione reductase (TR) inhibitor, exhibits an IC50 of 2.24 ± 0.52 μM. It effectively inhibits the growth of Leishmania, Trypanosoma cruzi, and Trypan...
T62210 Antileishmanial agent-10
Antileishmanial agent-10 (Compound 7h) is an antiprotozoal agent.
T40117 Antileishmanial agent-1
Antileishmanial agent-1 demonstrates activity against both L. amazonensis promastigotes (IC 50 = 15.52 μM) and intracellular amastigotes (IC 50 = 4.10 μM).
T72260 Antileishmanial agent-13
Antileishmanial agent-13, a quinoline-isatin hybrid, functions as an antileishmanial agent targeting the L. Major Leishmania strain through an anti-folate mechanism. This compound exhibits potent inhibition of both the p...
T83045 Antileishmanial agent-25 Parasite
Antileishmanial agent-25 (compound 24) exhibits selective activity against intracellular amastigotes, demonstrating an inhibitory concentration (IC50) of 6.63 μM [1].
Cat No. Product Name Synonyms Targets
T75502 Brazilein
Brazilein, an immunosuppressive compound extracted from Caesalpinia sappan L., effectively induces apoptosis in mouse spleen lymphocytes [1].

Natural Products

Brazilein
T75502
Synonym:
Target:

Recombinant Proteins

Species：
Human (2)
Expression System：
HEK293 Cells (2)
Tag：
C-His (1)
C-hFc (1)
Cat No. Product Name Species Expression System
TMPY-03757 FAM3C Protein, Human, Recombinant (hFc) Human HEK293 Cells
FAM3C Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.2 kDa and the accession number is Q92520.
TMPY-00299 FAM3C Protein, Human, Recombinant (His) Human HEK293 Cells
FAM3C Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.6 kDa and the accession number is Q92520.
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