14
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9144 | Telekin | Others | |
Telekin, a eudesmane-type sesquiterpene lactone compound isolated from Chinese folk medicine Carpesium divaricatum, has been reported to strongly inhibit the proliferation of cancer cells | |||
T3S0218 | Thonningianin A | Apoptosis , Others | |
1. Thonningianin A has anti-cancer activities.2. Thonningianin A represents a new potent glutathione S-transferase in vitro inhibitor.3. Thonningianin A has antioxidant property, involves radical scavenging, anti-superox... | |||
TN1881 | Lucidenic acid C | MMP | |
Lucidenic acid C has anti-invasive effect, it shows significant inhibitory effects on PMA-induced MMP-9 activity and invasion of HepG(2 )cells. | |||
T40723 | Bromoiodoacetamide | ||
Bromoiodoacetamide, an iodinated haloacetamide (I-HAcAm) compound, exhibits cytotoxic properties. Its mechanism of action involves the accumulation of reactive oxygen species (ROS) and induction of apoptosis in HepG-2 ce... | |||
T83366 | 3′,5-Dihydroxy-4′,6,7-trimethoxyflavanone | ||
3′,5-Dihydroxy-4′,6,7-trimethoxyflavanone, a natural product isolated from the fruits of Vitex rotundifolia, exhibits potent cytotoxic activity against A549 and HepG-2 cell lines [1]. | |||
T64047 | Topoisomerase II inhibitor 10 | ||
Topoisomerase II inhibitor 10 is a potent inhibitor of topoisomerase II (IC50: 7.45 μM). Topoisomerase II inhibitor 10 was able to arrest the cell cycle of HepG-2 cells in the G2-M phase and induce apoptosis. | |||
TN3528 | Bonducellpin D | Antifection | |
Bonducellpin D may show inhibitory activities on the Para3 virus. It also exhibits moderate activity against four tested human cancer cell lines, HepG-2, K562, HeLa, and Du145. | |||
T83087 | Anticancer agent 158 | ||
Anticancer agent 158 (compound 7c) demonstrates potent efficacy against various cancer cell lines, with IC50 values of 7.93 μM for HepG-2, 9.28 μM for MDA-MB-231, and 13.28 μM for HCT-116; however, it exhibits reduced po... | |||
TN4239 | Hydroxytanshinone IIA | Others | |
Hydroxytanshinone ⅡA has good antiproliferative effect on SGC-7901,HeLa, and HepG 2 cell, the values of IC50 are 4.18, 6.08 and10.20 uM, respectively; it has tumor cell proliferation inhibition significantly stronger tha... | |||
T82489 | EIF4E-IN-6 | ||
eIF4E-IN-6 (Compound 4b), a GMP analog, is designed to inhibit the eIF4E protein's ability to bind to cap mRNA. It demonstrates cytotoxic effects on Caco-2, HepG-2, and MCF-7 cell lines with IC50 values of 31, 27, and 21... | |||
TN2684 | 2,3,23-Trihydroxy-12-oleanen-28-oic acid | Others | |
2β,3β,23α-Trihydroxy-12-oleanen-28-oic acid shows cytotoxic activities to human lung adenocarcinoma(A-549)cell lines. 2α,3β,23-Trihydroxyolean-12-en-28-oic acid and 2α,3β,23-trihydroxyurs-12-en-28-oic acid exhibit cytoto... | |||
T60933 | B-Raf IN 7 | ||
B-Raf IN 7 (compound 6a) is a potent inhibitor of B-Raf with an IC 50 of 110.23 nM. B-Raf IN 7 has antitumor activity against colon carcinoma cells(HCT-116), mammary gland cells(MCF-7), hepatocellular carcinoma cells(HEP... | |||
T60727 | B-Raf IN 8 | ||
B-Raf IN 8 (compound 7g) is a potent inhibitor of B-Raf (IC 50 = 70.65 nM). B-Raf IN 8 shows antitumor activity which has IC 50 values of 9.78, 13.78, 18.52 and 29.85 μM against hepatocellular carcinoma (HEPG-2), colon ... | |||
T79256 | DPP-4-IN-8 | ||
DPP-4-IN-8 (compound 27) is a potent and selective inhibitor of dipeptidyl peptidase 4 (DPP4), with an inhibition constant (Ki) of 0.96 μM. It inhibits the dipeptidase activity of DPP4 in both Caco-2 and HepG-2 cells and... |