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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9756 | AZD-9574 | PARP | |
AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs. AZD-9574 exhibits anti-cancer activities and can be used in studies about HRD+ breast cancer and advanced solid malignancies. | |||
T61689 | ThrRS-IN-1 | ||
ThrRS-IN-1 (Compound 30d) is a potent inhibitor of threonyl-tRNA synthetase (ThrRS) from Salmonella enterica (Se ThrRS), exhibiting an IC50 of 1.4 μM and a Kd of 1.36 μM. It uniquely targets both the tRNA Thr and L-threo... | |||
T40561 | ThrRS-IN-2 | ||
ThrRS-IN-2 is an inhibitor of threonyl-tRNA synthetase (ThrRS), exhibiting an inhibition concentration (IC50) value of 56.5 ± 3.5 μM. | |||
T73123 | ThrRS-IN-3 | ||
ThrRS-IN-3, a threonyl-tRNA synthetase (ThrRS) inhibitor, exhibits high potency, demonstrated by an IC50 of 19 nM and a Kd of 34 nM against Salmonella enterica ThrRS. It also possesses antibacterial activities. | |||
T8800 | NSAH | 2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide | DNA/RNA Synthesis |
NSAH (2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide) is a nonnucleoside inhibitor of human ribonucleotide reductase (hRR).with cell-free IC50 of 32 μM and cell-based IC50 of ~250 nM, respectively... |