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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T32089 | HMS-I1 Hydrobromide | HMS-I1 HBr | |
HMS-I1 Hydrobromide is a probe that works by destroying heterochromatin mediated transcriptional gene silencing and is used for studies of heterochromatin formation and function. | |||
T32090 | HMS-I2 | HMSI2,HMS I2 | |
HMS-I2 is a chemical probe used to form heterochromatin. It works by disrupting heterochromatin mediated transcriptional gene silencing. | |||
T15159 | Dorzagliatin | HMS5552 | Glucokinase |
Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes. | |||
T28781 | Sinogliatin | HMS-5552,RO 5305552,HMS5552,RO5305552,HMS 5552,RO-5305552 | |
Sinogliatin, a glucokinase activator, is used potentially for the treatment of type 2 diabetes. | |||
T69365 | HMS607P03 | ||
HMS607P03 is an activator of SIRT1 which induces autophagic cell death via the AMPK-mTOR-ULK complex and induces mitophagy by the SIRT1-PINK1-Parkin pathway. HMS607P03 downregulates 14-3-3γ, catalase, profilin-1, and HSP... | |||
T0977 | Medrysone | Gimeracil,6α-Methyl-11β-hydroxyprogesterone | Glucocorticoid Receptor , Others |
Medrysone (6α-Methyl-11β-hydroxyprogesterone) is a topical, synthetic glucocorticoid with metabolic, anti-inflammatory and anti-allergic properties. Medrysone exerts its effect by interacting with specific intracellular ... |