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Search Results for " hdaci "

9

Compounds

Cat No. Product Name Synonyms Targets
T10603 BRD-6929 HIV Protease , HDAC
BRD-6929 is a selective, brain-penetrant HDAC1 and HDAC2 inhibitor (IC50:  1 and 8 nM). BRD-6929 (Cpd-60) shows high-affinity to HDAC1 and HDAC2 (Kis: 0.2 and 1.5 nM) [2]. BRD-6929 potentiates the efficacy of gnidimacrin...
T5347 CXD101 CXD-101 HDAC
CXD101 is a novel class I-selective HDACi (HDAC1 (IC50 : 63nM), HDAC2 (IC50 :570nM), HDAC3 (IC50 :550nM)). CXD101(CXD-101) has no activity against HDAC class II
T26355 ZYJ-34c ZYJ 34c,ZYJ34c
ZYJ-34c is a potent oral antitumor activities histone deacetylase inhibitor (HDACi).
T26356 ZYJ-34v
ZYJ-34v is an oral histone deacetylase inhibitor (HDACi) with potent antitumor activities.
T71917 FFK29
FFK29 is a synthetic class II HDACi (Histone deacetylase inhibitors) which have have recently emerged as novel therapeutic options for treating various protozoan and parasitic diseases. While these HDACi demonstrated a n...
T26354 ZYJ-25e ZYJ 25e
ZYJ-25e is an oral histone deacetylase inhibitor (HDACi) with potent antitumor activities.
T62041 XP5
XP5 is a potent, orally active HDAC6 inhibitor (IC50= 31 nM). XP5 inhibits the proliferation of various cancer cell lines including the HDACi-resistant YCC3/7 gastric cancer cells (IC50=0.16-2.31 μM).
T70190 Tinostamustine HCl
Tinostamustine, also known as EDO-S101, is an alkylatlng histone-deacetylase inhibitor (HDACi) fusion molecule. EDO-S101 is a functional pan-histone-deacetylase inhibitor and is assumed to potentiate the alkylating activ...
T61209 HDAC-IN-27
HDAC-IN-27 is a potent and orally active inhibitor of HDAC Class I (0.43 nM - 3.01 nM for HDAC1-3). HDAC-IN-27 shows activity against anti-acute myeloid leukemia (AML).
TargetMol