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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10603 | BRD-6929 | HIV Protease , HDAC | |
BRD-6929 is a selective, brain-penetrant HDAC1 and HDAC2 inhibitor (IC50: 1 and 8 nM). BRD-6929 (Cpd-60) shows high-affinity to HDAC1 and HDAC2 (Kis: 0.2 and 1.5 nM) [2]. BRD-6929 potentiates the efficacy of gnidimacrin... | |||
T5347 | CXD101 | CXD-101 | HDAC |
CXD101 is a novel class I-selective HDACi (HDAC1 (IC50 : 63nM), HDAC2 (IC50 :570nM), HDAC3 (IC50 :550nM)). CXD101(CXD-101) has no activity against HDAC class II | |||
T26355 | ZYJ-34c | ZYJ 34c,ZYJ34c | |
ZYJ-34c is a potent oral antitumor activities histone deacetylase inhibitor (HDACi). | |||
T26356 | ZYJ-34v | ||
ZYJ-34v is an oral histone deacetylase inhibitor (HDACi) with potent antitumor activities. | |||
T71917 | FFK29 | ||
FFK29 is a synthetic class II HDACi (Histone deacetylase inhibitors) which have have recently emerged as novel therapeutic options for treating various protozoan and parasitic diseases. While these HDACi demonstrated a n... | |||
T26354 | ZYJ-25e | ZYJ 25e | |
ZYJ-25e is an oral histone deacetylase inhibitor (HDACi) with potent antitumor activities. | |||
T62041 | XP5 | ||
XP5 is a potent, orally active HDAC6 inhibitor (IC50= 31 nM). XP5 inhibits the proliferation of various cancer cell lines including the HDACi-resistant YCC3/7 gastric cancer cells (IC50=0.16-2.31 μM). | |||
T70190 | Tinostamustine HCl | ||
Tinostamustine, also known as EDO-S101, is an alkylatlng histone-deacetylase inhibitor (HDACi) fusion molecule. EDO-S101 is a functional pan-histone-deacetylase inhibitor and is assumed to potentiate the alkylating activ... | |||
T61209 | HDAC-IN-27 | ||
HDAC-IN-27 is a potent and orally active inhibitor of HDAC Class I (0.43 nM - 3.01 nM for HDAC1-3). HDAC-IN-27 shows activity against anti-acute myeloid leukemia (AML). |