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Search Results for " hdac-in-27 "

4

Compounds

Cat No. Product Name Synonyms Targets
T61209 HDAC-IN-27
HDAC-IN-27 is a potent and orally active inhibitor of HDAC Class I (0.43 nM - 3.01 nM for HDAC1-3). HDAC-IN-27 shows activity against anti-acute myeloid leukemia (AML).
T8517 Belinostat PX105684,PXD101,PXD-101 HDAC , Autophagy
Belinostat (PXD101) is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.
T62649 HDAC-IN-34
HDAC-IN-34 (compound 27) is a potent inhibitor of HDAC that acts on HDAC1 (IC50: 0.022 μM) and HDAC6 (IC50: 0.45 μM). HDAC-IN-34 can bind to DNA and cause DNA damage. HDAC-IN-34 exhibits a significant anti-proliferative ...
T36629 Givinostat
Givinostat (ITF-2357) is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. Givinostat (ITF2357) suppresses total LPS-induced IL-1β production robustly compared with the reduction by ITF30...
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