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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6723 | Voglibose | AO 128,Glustat,Basen | Glucosidase |
Voglibose (Glustat), an N-substituted derivative of valiolamine, exhibits excellent inhibitory activity against α-glucosidases and action against hyperglycemia and various disorders caused by hyperglycemia. | |||
T11599 | Ibiglustat (L-Malic acid) | Ibiglustat L-Malic acid,GZ402671 (L-Malic acid),Venglustat (L-Malic acid),SAR402671 (L-Malic acid) | Transferase |
Ibiglustat (L-Malic acid) (Ibiglustat L-Malic acid) is a selective, brain-penetrant, and allosteric inhibitor of glucosylceramide synthase. Ibiglustat (L-Malic acid) can be used in studies about PD Parkinson’s disease, S... | |||
T3663 | Eliglustat | GENZ-112638,Genz 99067 | Transferase |
Eliglustat (Genz 99067) is an oral inhibitor of glucosylceramide synthase which is used in the therapy of type 1 Gaucher disease. | |||
TQ0155 | Miglustat hydrochloride | NB-DNJ hydrochloride,N-Butyldeoxynojirimycin hydrochloride,OGT918 hydrochloride | Transferase |
Miglustat hydrochloride (N-Butyldeoxynojirimycin hydrochloride) is an inhibitor of glucosylceramide synthase and can be used for studies about Type I Gaucher disease. | |||
T12039 | Miglustat | N-Butyldeoxynojirimycin,OGT918,NB-DNJ | Others |
Miglustat (NB-DNJ) is an alkylated product of imino sugar deoxynojirimycin.It is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1). | |||
T11176 | Eliglustat hemitartrate | Genz-112638,Eliglustat tartrate | Others |
Eliglustat hemitartrate (Genz-112638) , with an IC50 of 24 nM, is a specific, potent, oral active glucocerebral glycosidase inhibitor. | |||
T40542 | Sinbaglustat | ACT-519276,Sinbaglustat,OGT2378 | Transferase |
Sinbaglustat (OGT2378) (OGT2378) is a dual inhibitor of glucose ceramide synthetase (GCS) and non-lysosomal glucose ceramidase (GBA2).Sinbaglustat is an orally administered N-alkyl iminosugar that crosses the blood-brain... | |||
T4473 | Ibiglustat | Venglustat,SAR402671,GZ402671 | Transferase |
Ibiglustat (GZ402671) is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. Ibiglustat blocks the formation of glucosylceramide (GL-1), a key intermediate in the synthe... | |||
T70336 | Nizubaglustat | ||
Nizubaglustat acts as an inhibitor of Ceramide Glucosyltransferase, also known as Glucosylceramide Synthase (GCS), and additionally inhibits GBA2, which is involved in neuropathological lysosomal storage disorders. | |||
T39105 | Ibiglustat succinate | GZ402671succinate,Venglustat succinate,Ibiglustat succinate,SAR402671succinate | |
Ibiglustat (Venglustat) succinate is an orally active, brain-penetrant inhibitor of glucosylceramide synthase (GCS). It is utilized in the investigation of Gaucher disease type 3, Parkinson's disease associated with GBA ... | |||
T70347 | Ibiglustat hydrochloride | ||
Ibiglustat hydrochloride is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. | |||
T73716 | Miglustat-d | ||
Miglustat-d 9 (hydrochloride), a deuterium-labeled variant of Miglustat (hydrochloride), functions as a glucosylceramide synthase inhibitor. Its primary application is in the treatment of Type I Gaucher disease (GD1) [1]... |