glucosidase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T67898	α-Glucosidase-IN-22		Glucosidase
	α-Glucosidase-IN-22 is a selective inhibitor of α-glucosidase (IC50=0.64 μM). α-Glucosidase-IN-22 has antidiabetic activity and has potential in type 2 diabetes (T2DM) studies.		Glucosidase
T67728	α-Glucosidase-IN-23		Glucosidase
	α-Glucosidase-IN-23 is an orally active α-Glucosidase inhibitor. α-Glucosidase-IN-23 can decrease blood glucose by α-glucosidase inhibition (IC50= 4.48 μM).		Glucosidase
T41028	α-Glucosidase	α-D-Glucosidase
	α-Glucosidase (α-D-Glucosidase) is a carbohydrate hydrolyzing enzyme that catalyzes the release of α-glucose from the non-reducing end of the substrate. It plays a vital role in facilitating glucose absorption by the sma...
T60715	α-Glucosidase-IN-4		Glucosidase
	α-Glucosidase-IN-4 is a potent α-glucosidase inhibitor with antihypertensive and hypoglycemic activity.		Glucosidase
T76110	β-Glucosidase
	β-Glucosidase, a pivotal enzyme in cellulose degradation, belongs to the extensive family of glycoside hydrolases. It plays a crucial role in breaking down cellulose in soils and holds promise for assessing biological so...
T3S0860	Gitogenin		UGT
	1. Gitogenin, tigogenin, and solasodine are novel selective inhibitors of UGT1A4, and do not inhibit the activities of major human CYP isoforms. 2. Gitogenin and (25S)-5α-furastan-3β, 22, 26-triol are the inhibitors of e...		UGT
T63562	α-Glucosidase-IN-14
	α-Glucosidase-IN-14 is a potent inhibitor of α-glucosidase (IC50: 5.22 μM).
T62222	α-Glucosidase-IN-11
	α-Glucosidase-IN-11 is a highly permeable competitive inhibitor of α-glucosidase (IC50: 0.56 μM). α-Glucosidase-IN-11 binds to the Trp residue in α-glucosidase and has a regulatory effect on protein folding and can be us...
T61519	α-Glucosidase-IN-18
	α-Glucosidase-IN-18 (7B) is an orally active inhibitor of α-glucosidase, displaying an IC 50 value of 3.96 μM. This compound exhibits antidiabetic properties [1].
T61166	α-Glucosidase-IN-16
	α-Glucosidase-IN-16 is a highly effective and orally bioavailable inhibitor of α-glucosidase, displaying a remarkable IC50 value of 3.28 μM. This compound demonstrates the ability to significantly decrease blood glucose ...
T61124	α-Glucosidase-IN-9
	α-Glucosidase-IN-9 (compound 7) is a highly potent α-glucosidase inhibitor with an IC50 of 55.6 μM, making it suitable for type II diabetes research [1].
T60389	α-Glucosidase-IN-5
	α-Glucosidase-IN-5 (compound 8) is isolated from a twig extract of Polyalthia cinnamomea which is a potent α-glucosidase inhibitor with an IC50 of 57.9 µM. α-Glucosidase-IN-5 has the potential for the research of diabete...
T79237	α-Glucosidase-IN-27		Glucosidase
	α-Glucosidase-IN-27 (compound 8l), an α-glucosidase inhibitor with an IC50 value of 25.78 μM, demonstrates potential for research into type 2 diabetes (D2M) [1].		Glucosidase
T78794	α-Glucosidase-IN-31		Glucosidase
	α-Glucosidase-IN-31 (compound R1) is a potent oral α-Glucosidase inhibitor with an IC50 of 10.1 μM, demonstrating significant blood glucose reduction and antidiabetic activity [1].		Glucosidase
T79700	α-Glucosidase-IN-32		Glucosidase
	α-Glucosidase-IN-32 (compound f26) is a reversible, noncompetitive inhibitor of α-glucosidase that is orally active and exhibits an IC50 of 3.07 μM. It forms a complex with α-glucosidase via hydrogen bonding and hydropho...		Glucosidase
T80709	α-Glucosidase-IN-41		Glucosidase
	α-Glucosidase-IN-41 (compound 5o), a potent inhibitor of α-glucosidase, induces alterations in the secondary structure of the enzyme, thereby impeding its catalytic function. This compound is utilized in the study of dia...		Glucosidase
T78740	α-Glucosidase-IN-28		Glucosidase
	α-Glucosidase-IN-28 (Compound 18) is an α-glucosidase inhibitor with an IC50 of 0.62 μM and Ki value of 3.93 μM. It interacts with the enzyme's original binding site (OBS) and establishes multiple hydrophobic interaction...		Glucosidase
T63310	α-Glucosidase-IN-6
	α-Glucosidase-IN-6 is a competitive inhibitor of α-glucosidase (IC50: 5.69 μM) and exhibits potential for anti-diabetic studies.
T61503	α-Glucosidase-IN-15
	α-Glucosidase-IN-15 (Compound 14B) exhibits potent inhibitory activity against α-glucosidase, with an IC50 value of 3.34 μM. It possesses antidiabetic properties [1].
T62972	α-Glucosidase-IN-17
	α-Glucosidase-IN-17 (Compound 12B) is a potent and orally active inhibitor of α-glucosidase, demonstrating antidiabetic activity with an inhibitory concentration (IC50) of 3.79 μM [1].