3
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4409 | Gilteritinib | ASP2215 | FLT , TAM Receptor , c-Kit |
Gilteritinib (ASP2215) is a potent inhibitor at the FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM, respectively). In preClinicalal studies, gilteritinib showed strong an... | |||
T71973 | Gilteritinib hemifumarate | ASP2215 hemifumarate | FLT , TAM Receptor |
Gilteritinib hemifumarate (ASP2215 hemifumarate) is a potent ATP-competitive dual FLT3 (IC50: 0.29 nM) and AXL (IC50: 0.73 nM) inhibitor for the treatment of relapsed or refractory FLT3 mutant AML. | |||
T71117 | AZD5248 | ||
AZD-5248 is a potent, selective, first generation, oral inhibitor of dipeptidyl peptidase 1 (DPP1). |