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Search Results for " gas6 "

5

Compounds

Cat No. Product Name Synonyms Targets
T7425 RU-301 TAM Receptor
RU-301 is a novel pan-tam inhibitor
T16806 RU-302 [2-[(3,5-dimethyl-1,2-oxazol-4-yl)methylsulfanyl]phenyl]-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone TAM Receptor
RU-302 is a pan inhibitor of TAM Receptor blocking the interface between the TAM Ig1 ectodomain and the Gas6 Lg domain. RU-302 effectively blocks the activation of Gas6-inducible AXL and suppresses lung cancer tumor grow...
T8181 Poricoic acid A Poricoic acid A(F) Others
Poricoic acid A (Poricoic acid A(F)) is a natural product with antitumor activity. It also enhances melatonin inhibition of AKI-to-CKD transition by regulating the Gas6/AxlNFκB/Nrf2 axis.
T73310 AXL-IN-14 TAM Receptor
AXL-IN-14 is a potent, orally active inhibitor of AXL with an IC50 of 0.8 nM that effectively suppresses Gas6/AXL-mediated cell migration and invasion, reduces the expression of p-AXL and p-AKT proteins, and demonstrates...
T76723 Tilvestamab
Tilvestamab (BGB149), a humanized anti-AXL antibody, effectively blocks AXL-mediated cell signaling, significantly reduces Gas6-induced AXL activation, and inhibits downstream AKT phosphorylation in 786-0-Luc RCC cells. ...
TargetMol