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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3113 | Foretinib | GSK089,EXEL-2880,GSK1363089,XL880 | VEGFR , Tie-2 , c-Met/HGFR |
Foretinib (GSK1363089) is a broad-spectrum tyrosine kinase inhibitor with IC50s of 0.4 nM and 0.9 nM for Met and KDR. | |||
T36246 | SJF 8240 | ||
c-MET degrader. Comprises MET inhibitor foretinib (GSK 1363089; Cat. No. 6056) joined by a linker to a von Hippel-Lindau (VHL) recruiting ligand. Degrades c-MET within 6 hours in vitro. Inhibits agonist-driven AKT phosph... |