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Search Results for " gne-207 "

2

Compounds

Cat No. Product Name Synonyms Targets
T15399 GNE-207 Epigenetic Reader Domain
GNE-207 is a selective and orally bioavailable inhibitor of the bromodomain of CBP (IC50: 1 nM). It has a selective index of >2500-fold against BRD4 (1). GNE-207 displays excellent CBP potency (EC50: 18 nM for MYC expres...
T79230 JET-209 PROTACs
JET-209 is a potent proteolysis-targeting chimera (PROTAC) that effectively degrades CBP/p300, exhibiting half-maximal degradation concentration (DC50) values of 0.05 nM for CBP and 0.2 nM for p300. The compound comprise...
TargetMol