g4-dna — TargetMol Chemicals

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Search Results for " g4-dna "

Compounds

Cat No.	Product Name	Targets
T18883	2-Di-1-ASP	Others
	2-Di-1-ASP is a mono-stryryl dye and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. It has selective for G-quadruplex (G4) and double-stranded DNA.	Others
T13584	BMVC-8C3O	DNA/RNA Synthesis
	BMVC-8C3O, a DNA G-quadruplex (G4) ligand, induces the topological conversion from non-parallel to parallel forms in human telomeric DNA G4s.	DNA/RNA Synthesis
T72571	Antitumor agent-84
	Antitumor Agent-84, a G-quadruplex (G4)-ligand, stabilizes various G4-DNA structures, demonstrating highly effective antitumor properties.
T72572	Antitumor agent-85
	Antitumor agent-85, a G-quadruplex (G4)-ligand, stabilizes various G4-DNA structures and possesses potent anti-tumor properties.
T10574	BMVC	Telomerase
	BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities. BMVC inhibits Taq DNA polymerase (IC50: ~2.5 μM).	Telomerase
T75527	Chrexanthomycin C
	Chrexanthomycin C, an orally active marine-derived natural product, exhibits significant bioactivities and shows a binding affinity for DNA [(G4C2)4 G4] with a dissociation constant (Kd) of 2.8 mM. This compound holds po...
T78846	EP12	Apoptosis
	EP12, a c-Myc inhibitor and G4 stabilizer, induces apoptosis and DNA damage in multiple myeloma cells while obstructing P65/P50 nuclear translocation by disrupting the NF-κB signaling pathway, effectively inhibiting mult...	Apoptosis