fluconazole — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1388	Fluconazole	UK-49858	Antibiotic , Antifection , Antifungal
	Fluconazole (UK-49858) is a triazole antifungal agent that is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS.		Antibiotic , Antifection , Antifungal
T21881	Fluconazole hydrate
	Fluconazole (hydrate) is a triazole antifungal agent used for the oral treatment and prevention of both superficial and systemic fungal infections, including but not limited to balanitis, various Candida infections, Cryp...
T61960	Fluconazole mesylate
	Fluconazole (mesylate) is a triazole antifungal drug. Fluconazole (mesylate) can used in the treatment and prevention of superficial and systemic fungal infections
T27617	Inz-1		P450
	Inz-1 is an effective and fungal-selective inhibitor of mitochondrial cytochrome bc1 with IC50s of 8.092 and 45.320 μM for yeast and human. Inz-1 reverses Fluconazole or other triazole antifungals’ resistance in the path...		P450
T5328	Fosfluconazole		Antifungal
	Fosfluconazole is water-soluble phosphate prodrug of fluconazole. Fluconazole is an antifungal drug.		Antifungal
T11991	Mefentrifluconazole		P450 , Antifungal
	Mefentrifluconazole is a potent, selective and orally active fungal CYP51 (Kd= 0.5 nM) inhibitor, but shows less inhibitory activity on human aromatase (IC50=0.92 μM). Mefentrifluconazole is a novel azole derivative and ...		P450 , Antifungal
T2213	Terconazole	Gyno-Terazol,Terazol 3,Terazol 7,Triaconazole,R42470	Antifection , Antifungal
	Terconazole (Terazol 7) is a synthetic triazole derivative structurally related to fluconazole, antifungal Terconazole seems to disrupt cell wall synthesis by inhibiting biosynthesis of ergosterol or other sterols, damag...		Antifection , Antifungal
T8826	3-AMINO-1,2,4-TRIAZINE		Others
	3-AMINO-1,2,4-TRIAZINE is an aromatic bioactive compound. It has been used to synthesize a variety of drugs, including the antifungal drug fluconazole, the anti-inflammatory drug ibuprofen and the anticancer drug paclita...		Others
T38240	2,6-Dichlorodiphenylamine		Antibacterial
	2,6-Dichlorodiphenylamine is an analogue of Diclofenac Sodium and has anti-Candida albicans activity. Diclofenac Sodium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1...		Antibacterial
T35297	ZD 0870	D 0870,D0870,ZD0870
	ZD 0870, used to treat infections caused by fluconazole-resistant candida albicans.
T63478	Antifungal agent 12
	Antifungal agent 12 is a new fluconazole-like compound that exhibits good antifungal effects.
T79709	PK-10
	PK-10, when combined with Fluconazole, exhibits potent synergistic antifungal activity against multiple Fluconazole-resistant Candida albicans strains. This compound impedes hyphae formation, stimulates reactive oxygen s...
T63802	Antifungal agent 35
	Antifungal agent 35 is an effective antifungal agent that potentiates the antifungal activity of fluconazole against C. albicans.
T63157	Antifungal agent 16
	Antifungal agent 16 has antimicrobial activity comparable to that of ciprofloxacin and has higher antifungal activity than fluconazole.
T79413	Antifungal agent 73
	Antifungal agent 73 (compound A32) effectively combats azole-resistant candidiasis by disrupting the fungal cell wall and membrane. It demonstrates potent in vivo activity against pathogenic fungi, including fluconazole-...
T62167	BI-10
	BI-10 is an antifungal compound that, in combination with fluconazole, inhibits mycelial growth, accumulates ROS, reduces mitochondrial membrane potential (MMP) and alters membrane permeability.
T61188	Chitin synthase inhibitor 2
	Chitin synthase inhibitor 2 (compound 2b) is a highly potent inhibitor of chitin synthase, with an IC50 value of 0.09 mM and a K i value of 0.12 mM. This compound exhibits antimicrobial activities in vitro and demonstrat...
T79384	Antifungal agent 72
	Antifungal agent 72 (Compound B8) demonstrates potent activity by inhibiting the efflux pump function and downregulating resistance-associated genes via disruption of the Pdr1-KIX interaction (K i : 11.7 μM). It exhibits...
T64235	Antifungal agent 25
	Antifungal agent 25 is an effective, broad-spectrum, metabolically stable antifungal agent in vivo. antifungal agent 25 exhibits antifungal effects against both Candida albicans and fluconazole-resistant Candida albicans...
T75178	Antifungal agent 55
	Antifungal agent 55 (Compound A07) effectively inhibits Fluconazole-resistant strains of Candida albicans, demonstrating greater efficacy than Miconazole. It exhibits minimum inhibitory concentrations (MIC) values rangin...