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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2061 | APY0201 | PI3K , Interleukin | |
APY0201 is a effective, highly specific, ATP-competitive PIKfyve inhibitor (IC50: 5.2 nM). It can interrupt the conversion of phosphatidylinositol 3-phosphate (PtdIns3P) to PtdIns(3, 5)P2. | |||
T33467 | MOMIPP | PI3K | |
MOMIPP is a PIKfyve inhibitor and a macropinocytosis inducer. MOMIPP readily penetrates the blood-brain barrier and is moderately effective in suppressing progression of intracerebral glioblastoma xenografts[1][2]. | |||
T21992 | Vacuolin-1 | PI3K , Autophagy | |
Vacuolin-1 is a cell-permeable inhibitor of Ca2+ dependent fusion of lysosomes to the cell membrane. It acts by inhibiting release of lysosomal content.vacuolin‐1 is a potent and selective PIKfyve inhibitor and inhibits ... | |||
T6110 | YM-201636 | Influenza Virus , PI3K , Autophagy | |
YM201636 (IC50=33 nM), a specific PIKfyve inhibitor, is less effective to p110α and insensitive to Fabl, which is yeast orthologue. | |||
T2018 | Apilimod | STA 5326 | IL Receptor , PI3K , Interleukin |
Apilimod (STA 5326) inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis. | |||
T3533 | Apilimod mesylate | STA 5326 mesylate | IL Receptor , PI3K , Interleukin |
Apilimod mesylate (STA 5326 mesylate) is a potent IL-12/IL-23 inhibitor. |