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Search Results for " fab1 "

6

Compounds

Cat No. Product Name Synonyms Targets
T2061 APY0201 PI3K , Interleukin
APY0201 is a effective, highly specific, ATP-competitive PIKfyve inhibitor (IC50: 5.2 nM). It can interrupt the conversion of phosphatidylinositol 3-phosphate (PtdIns3P) to PtdIns(3, 5)P2.
T33467 MOMIPP PI3K
MOMIPP is a PIKfyve inhibitor and a macropinocytosis inducer. MOMIPP readily penetrates the blood-brain barrier and is moderately effective in suppressing progression of intracerebral glioblastoma xenografts[1][2].
T21992 Vacuolin-1 PI3K , Autophagy
Vacuolin-1 is a cell-permeable inhibitor of Ca2+ dependent fusion of lysosomes to the cell membrane. It acts by inhibiting release of lysosomal content.vacuolin‐1 is a potent and selective PIKfyve inhibitor and inhibits ...
T6110 YM-201636 Influenza Virus , PI3K , Autophagy
YM201636 (IC50=33 nM), a specific PIKfyve inhibitor, is less effective to p110α and insensitive to Fabl, which is yeast orthologue.
T2018 Apilimod STA 5326 IL Receptor , PI3K , Interleukin
Apilimod (STA 5326) inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis.
T3533 Apilimod mesylate STA 5326 mesylate IL Receptor , PI3K , Interleukin
Apilimod mesylate (STA 5326 mesylate) is a potent IL-12/IL-23 inhibitor.
TargetMol