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Search Results for " flt3-in-19 "

5

Compounds

Cat No. Product Name Synonyms Targets
T78176 FLT3-IN-19
FLT3-IN-19 (Comp 50) is a potent, selective inhibitor of FLT3, demonstrating an IC50 value of 0.213 nM, and is applicable in research pertaining to acute myeloid leukemia (AML) [1].
T6020 Pacritinib SB1518 FLT , Tyrosine Kinases , JAK
Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).
T62824 FLT3/ITD-IN-3
FLT3/ITD-IN-3 (Compound 19) is a potent inhibitor of FLT3-ITD, acting on FLT3D835Y (IC50: 0.3 nM), FLT3 (IC50: 0.4 nM) and FLT3-ITD (IC50: 0.9 nM). FLT3/ITD-IN-3 showed potent inhibition of FLT3 phosphorylation and was e...
T61755 E6201
E6201 (ER-806201) is a potent dual kinase inhibitor targeting MEK1 and FLT3, inhibiting their activities in an ATP-competitive manner. It effectively suppresses MEK1-induced ERK2 phosphorylation (IC50 = 5.2 nM), MKK4-ind...
T64283 Pacritinib hydrochloride
Pacritinib hydrochloride is a potent inhibitor of wild-type JAK2 (IC50: 23 nM) and the JAK2V617F mutant (IC50: 19 nM). Pacritinib hydrochloride can be used in the study of acute myeloid leukaemia (AML) and myelofibrosis ...
TargetMol