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Search Results for " ensartinib "

3

Compounds

Cat No. Product Name Synonyms Targets
T37585 Ensartinib
Ensartinib (X-396) is a potent and dual ALK/MET inhibitor with IC50s of <0.4 nM and 0.74 nM, respectively. The ability of Ensartinib (X-396) to inhibit the growth of different cancer cell lines harboring ALK fusions or ...
T22324 Ensartinib hydrochloride Ensartinib dihydrochloride,X-396 dihydrochloride Others , Trk receptor , c-Met/HGFR , ALK
Ensartinib hydrochloride (X-396 dihydrochloride) is a potent new-generation ALK inhibitor with high activity against CNS metastases and a broad range of known crizotinib-resistant ALK mutations. It potently inhibits both...
T3550 X-376 Ensartinib,X-396 c-Met/HGFR , ALK
X-376 (Ensartinib) is an orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with potential antineoplastic activity. Upon oral administration, X-396 binds to and inh...
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