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Search Results for " endocytosis,dynamin,gtpase "

8

Compounds

Cat No. Product Name Synonyms Targets
T6822 Hydroxy-Dynasore Dyngo-4a Dynamin
Hydroxy-Dynasore (Dyngo-4a) , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM, respectively.
T64369 Dynamin IN-2 Dynamin
Dynamin IN-2 (compound 43) is a Wiskostatin analogue. Dynamin IN-2 is a potent dynamin inhibitor (dynamin I GTPase, IC50= 1.0 μM). Dynamin IN-2 blocks clathrin mediated endocytosis (CME) (IC50= 9.5 μM).
TP1907 DynaMin inhibitory peptide, myristoylated
Cell-permeable version of dynamin inhibitory peptide, an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. Reduces NMDA receptor internalization.
T38407 RTIL 13
RTIL 13 is a highly effective inhibitor of dynamin GTPase, exhibiting an IC50 value of 2.3 μM for dynamin I GTPase. Furthermore, it selectively interacts with the pleckstrin homology lipid binding domain. This compound e...
TP2039 Dynamin inhibitory peptide, myristoylated (control)
Control peptide version of dynamin inhibitory peptide, myristoylated, an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. In contrast to dynamin inhibit...
T61488 Dynole 2-24
Dynole 2 24 is an indole-based dynamin GTPase inhibitor ( IC 50 =0.56 μM for dynamin I). Dynole 2 24 is nontoxic and shows increased potency against dynamin I and II in vitro and in cells (IC (CME) =1.9 μM). Dynole 2 2...
T72894 Clathrin-IN-2
Clathrin-IN-2 is a potent inhibitor of clathrin-mediated endocytosis (CME), demonstrating an IC50 value of 2.3 μM. Additionally, it exhibits inhibitory effects on dynamin I GTPase, with an IC50 of 7.7 μM.
T83891 Sulfonadyn-47
Sulfonadyn-47 is a dynamin inhibitor that effectively inhibits dynamin GTPase activity with an IC50 of 3.5 µM in cell-free assays. Additionally, it disrupts clathrin-mediated endocytosis in U2OS cells (IC50 = 27.3 µM) an...
TargetMol