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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2335 | Ebastine | Ebastel,LAS-W 090,Ebastin,Kestine,RP64305 | Histamine Receptor |
Ebastine (Kestine) (trade names Evastin, Kestine, Ebastel, Aleva) is a non-sedating H1 antihistamine. It does not penetrate the blood-brain barrier and thus allows an effective block of the H1 receptor in peripheral tiss... | |||
T10680 | Carebastine | Histamine Receptor | |
Carebastine, the active metabolite of Ebastine, is an antagonist of the histamine H1 receptor. | |||
T2640 | Rebastinib | DCC2036,DCC 2036,DCC-2036 | Apoptosis , FLT , Bcr-Abl , Src |
DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC, HCK, FGR, FLT3, KDR, and Tie-2, and low activity to c-Kit. Re... | |||
T37515 | Hydroxy Ebastine | ||
Hydroxy Ebastine is an ebastine metabolite. Ebastine undergoes rapid first-pass metabolism by the cytochrome P450 isoform CYP2J2 to form hydroxy ebastine which is then metabolized by CYP2J2 and CYP3A4 to form carebastine... |