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Search Results for " dpre1-in-1 "

10

Compounds

Cat No. Product Name Synonyms Targets
T62741 DprE1-IN-1
DprE1-IN-1 is a potent, orally active DprE1 inhibitor that exhibits good hepatocyte stability, low cytotoxicity and low hERG channel inhibition. DprE1-IN-1 has good anti-branched bacilli activity in macrophages, reducing...
T3224 TBA-7371 AZ 7371,DprE1-IN-1 Antibacterial , PDE , DprE1
TBA-7371 (DprE1-IN-1) is a potent inhibitor of DprE1 and PDE6.
T4044 DprE1-IN-2 Antibacterial , DprE1
DprE1-IN-2 is an effective DprE1 inhibitor.
T27206 DprE1-IN-377790
DprE1-IN-377790 is a novel DprE1 inhibitor, killing M. tuberculosis.
T78883 DprE1-IN-9
DprE1-IN-9 (compound B18) is an efficient reversible inhibitor of DprE1, interacting with the enzyme's receptor cavity. It exhibits potent antimycobacterial properties, demonstrating activity against both non-pathogenic ...
T79442 DprE1-IN-7
DprE1-IN-7 (Compound 64) is a DprE1 inhibitor with potent anti-tuberculosis (TB) activity, demonstrating a minimum inhibitory concentration (MIC) of 1 μM against the Mtb H37Rv strain. It exhibits antimycobacterial effect...
T79628 DprE1-IN-8 Antibiotic
DprE1-IN-8 is a potent inhibitor of DprE1, exhibiting an IC50 of less than 0.75 μM. It has demonstrated significant activity against Mtb H37Rv, with an IC50 value of 6 nM, making it applicable in tuberculosis research [1...
T79440 DprE1-IN-5
DprE1-IN-5 (Compound 10), a potent DprE1 inhibitor, exhibits anti-TB activity with an MIC of 4 μM against the Mtb H37Rv strain and demonstrates antimycobacterial efficacy against drug-resistant strains. Additionally, it ...
T79441 DprE1-IN-6
DprE1-IN-6 (Compound 56) is a DprE1 inhibitor with demonstrated anti-TB activity, exhibiting a minimum inhibitory concentration (MIC) of 1 μM against the Mtb H37Rv strain, along with efficacy against drug-resistant mycob...
T37880 OPC-167832
OPC-167832 is a potent and orally active dprE1 Inhibitor with an IC50 of 0.258 μM. OPC-167832 has antituberculosis activity and can be used for the research of tuberculosis caused by Mycobacterium tuberculosis[1]. OPC-16...
TargetMol