3
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T79920 | Debrisoquin | Debrisoquine,Ro 5-3307/1,Isocaramidine | SARS-CoV |
Debrisoquin (Isocaramidine) is a TMPRSS2 inhibitor that prevents SARS-CoV-2 from entering human lung cells through TMPRSS2-dependent pathways, exhibiting an IC50 value of 22μM. It holds potential for use in antiviral res... | |||
T31272 | Debrisoquin sulfate | Tendor,Isocaramidine,Debrisochinum,Debrisoquine,Debrisoquin,Debrisoquina | |
Debrisoquine is an antihypertensive drug similar to guanethidine. | |||
TMA2106 | (-)-Sparteine | P450 | |
Sparteine is a class 1a antiarrhythmic agent, a sodium channel blocker. The deficient debrisoquine hydroxylation of Sparteine is due to the absence of P-450IID1 protein in the livers of poor metabolizers. |