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Debrisoquin sulfate

Catalog No. T31272 CAS 581-88-4

Synonyms: Tendor, Isocaramidine, Debrisochinum, Debrisoquine, Debrisoquin, Debrisoquina

Debrisoquine is an antihypertensive drug similar to guanethidine.

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Debrisoquin sulfate, CAS 581-88-4

Pack Size	Availability	Price/USD	Quantity
2 mg	5 days	$ 49.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Debrisoquine is an antihypertensive drug similar to guanethidine.

Synonyms	Tendor, Isocaramidine, Debrisochinum, Debrisoquine, Debrisoquin, Debrisoquina
Molecular Weight	273.31
Formula	C10H15N3O4S
CAS No.	581-88-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Laine K, Tybring G, Härtter S, Andersson K, Svensson JO, Widén J, Bertilsson L. Inhibition of cytochrome P4502D6 activity with paroxetine normalizes the ultrarapid metabolizer phenotype as measured by nortriptyline pharmacokinetics and the debrisoquin test. Clin Pharmacol Ther. 2001 Oct;70(4):327-35. PubMed PMID: 11673748. 2. Hamelin BA, Turgeon J, Vallée F, Bélanger PM, Paquet F, LeBel M. The disposition of fluoxetine but not sertraline is altered in poor metabolizers of debrisoquin. Clin Pharmacol Ther. 1996 Nov;60(5):512-21. PubMed PMID: 8941024. 3. Lautenschlager MT, Viktor S, Müller UA, Hoffmann A. [Comparison of serum concentrations of caffeine, 4-methylaminoantipyrine, sulfamethazine and debrisoquin following oral administration of these substances as a cocktail in type II diabetics before and after insulin therapy]. Pharmazie. 1996 Oct;51(10):750-3. German. PubMed PMID: 8999440. 4. Marandi T, Dahl ML, Kiivet RA, Rägo L, Sjöqvist F. Debrisoquin and S-mephenytoin hydroxylation phenotypes and CYP2D6 genotypes in an Estonian population. Pharmacol Toxicol. 1996 May;78(5):303-7. PubMed PMID: 8737964.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Debrisoquin sulfate 581-88-4 Tendor Isocaramidine Debrisochinum Debrisoquin Sulfate Debrisoquine Debrisoquin Debrisoquina inhibitor inhibit

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