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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T60286 | DHFR-IN-2 | ||
DHFR-IN-2 (compound 4e) is a potent and uncompetitive inhibitor for MtDHFR with an IC 50 of 7 μM. The enzyme dihydrofolate reductase from M.tuberculosis (MtDHFR) has a high unexploited potential to be a target for new dr... | |||
T61229 | VEGFR-2/DHFR-IN-2 | ||
VEGFR-2/DHFR-IN-2 (compound 5b) is a dual inhibitor targeting VEGFR-2 and DHFR, with respective IC50 values of 0.623 μM and 9.085 μM. It demonstrates potent cytotoxicity against C26, HepG2, and MCF7 cancer cell lines, wi... | |||
T61489 | VEGFR-2/DHFR-IN-1 | ||
VEGFR-2/DHFR-IN-1 (compound 8b) is a chemical inhibitor targeting VEGFR-2 and DHFR, exhibiting IC50 values of 0.384 μM and 7.881 μM, respectively. It demonstrates effective antibacterial properties against a range of pat... | |||
T82493 | EGFR/HER2/DHFR-IN-2 | EGFR | |
EGFR/HER2/DHFR-IN-2 (Compound 4b) serves as an inhibitor for EGFR, HER2, and DHFR, with IC50 values of 0.248, 0.156, and 0.138 μM, respectively. It exhibits anticancer activity, displaying IC50 values of 9.14, 7.33, 14.1... |