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Cat No. | Product Name | Synonyms | Targets |
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T14362 | AY 9944 | Others | |
AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme (IC50=13 nM). At high doses, AY 9944 inhibits also in cultured embryos sterol Δ7-Δ8 isomera... | |||
T20999 | 1-(2,3-Dichlorphenyl)-piperazine | DCPP | Others |
1-(2,3-Dichlorphenyl)-piperazine (DCPP) is a potent DHCR7 inhibitor. DHCR7 is the last enzyme in cholesterol biosynthesis. | |||
T8968 | ML299 | VU0463568,ML-299 | Phospholipase |
ML299 (VU0463568) is a dual PLD1/2 inhibitor (PLD1 and PLD2, IC50 of 6 nM, 20 nM, respectively). |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00218 | DHCR7 Protein, Bovine, Recombinant (His) | Bovine | E. coli |
7-dehydrocholesterol reductase of the cholesterol biosynthetic pathway reducing the C7-C8 double bond of cholesta-5,7-dien-3beta-ol (7-dehydrocholesterol/7-DHC) and cholesta-5,7,24-trien-3beta-ol, two intermediates in th... |