dc1 — TargetMol Chemicals

Cat No.	Product Name	Targets
T10970	DC1	Others
	DC1 can be used to synthesize antibody-drug conjugates targeted to the treatment of cancer, is an ADC cytotoxin, similar to the small groove-binding DNA alkylating agent CC-1065.	Others
T2311	LDC1267	TAM Receptor
	LDC1267 is a excellently specific TAM(Tyro3, Axl and Mer) kinase inhibitor, for Mer( IC50<5 nM), Tyro3(IC50=8 nM), and Axl(IC50=29 nM).	TAM Receptor
T10969	DC1SMe	Others
	DC1 is an ADC cytotoxin, similar to the small groove-binding DNA alkylating agent CC-1065. DC1 can be used to synthesize antibody-drug conjugates targeted to the treatment of cancer. DC1Sme is a DC1 derivative with IC50 ...	Others
T74701	A18-Iso5-2DC18
	A18-Iso5-2DC18 (compound A18), a lipidoid, enhances mRNA protein expression and induces a robust immune response [1].
T82043	Iso5-2DC18
	Iso5-2DC18, a lipid, is utilized in the synthesis of amine-containing lipids, which are instrumental in mRNA delivery, activation of the stimulator of interferon genes (STING) pathway, and demonstration of anti-tumor imm...
T74972	A2-Iso5-4DC19
	A2-Iso5-4DC19, a lipidoid compound, effectively facilitates the delivery of agents, including polynucleotides, to cells [1].
T80178	Dc1a	Sodium Channel
	Dc1a, a toxin isolated from the desert bush spider Diguetia canities [1], potently facilitates the opening of the German cockroach Na v channel (BgNa v 1).	Sodium Channel
T10971	DC10SMe	Others
	DC10SMe is a DNA alkylating agent that can be used in the synthesis of antibody-drug conjugates (ADC). The IC50 of DC10SMe for Ramos, Namalwa and HL60 / s cancer cells were 15 pM, 12 pM and 12 pM, respectively.	Others
T10974	DC41	Others
	DC41 is a derivative of DC1. DC1 is a simplified analogue of CC-1065, an antibody conjugate of cytotoxic DNA alkylating agents, used for targeted treatment of cancer.	Others
T10973	DC41SMe	Others
	DC41SMe is a DC1 derivative that is cytotoxic to Ramos, Namalwa and HL60 / s with IC50s ranging from 18-25 pM. DC1 is a simplified analogue of CC-1065, an antibody conjugate of cytotoxic DNA alkylation molecules, used fo...	Others
T82047	IRGRILHDGAYSLTLQGLGIH TFA
	IRGRILHDGAYSLTLQGLGIH TFA, a multi-epitope class II rat HER2/neu peptide, is utilized in the study of class II HER2-DC1 vaccines [1].
T81112	SPPHPSPAFSPAFDNLYYWDQ
	SPPHPSPAFSPAFDNLYYWDQ is a multi-epitope class II rat HER2/neu peptide applicable in the investigation of class II HER2-DC1 vaccine studies [1].
T81111	SPPHPSPAFSPAFDNLYYWDQ TFA
	SPPHPSPAFSPAFDNLYYWDQ TFA is a multi-epitope, class II rat HER2/neu peptide designed for research on the class II HER2-DC1 vaccine [1].
T82048	IRGRILHDGAYSLTLQGLGIH
	IRGRILHDGAYSLTLQGLGIH is a multi-epitope class II rat HER2/neu peptide utilized in research for the class II HER2-DC1 vaccine studies [1].
T10968	DC0-NH2	Others
	The cytotoxicity of DC0-NH2 is 1000 times that of commonly used anti-cancer drugs (such as doxorubicin). It is the effect part of ADC. It is a simplified simulation of DC1 and has better stability. DC0-NH2 can bind to th...	Others