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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T60024 | CFT7455 | Cemsidomide | Ligand for E3 Ligase |
CFT7455 (Cemsidomide) is an anti-cancer agent showing high affinity to the cereblon E3 ligase with a Kd of 0.9 nM. CFT7455 is an orally active degrader of zinc finger transcription factors Ikaros (IKZF1), and Aiolos (IKZ... | |||
T63024 | (Rac)-CFT7455 | ||
(Rac)-CFT7455 is an Ikaros/Aiolos degradation agent that acts via the ubiquitin proteasome pathway and is able to act on NCIH929.1 cells (GI50: 0.05 nM). (Rac)-CFT7455 is a racemic isomer of CFT7455 and has anticancer ac... |