cck-b — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10707	CCK-B Receptor Antagonist 2		Others
	CCK-B Receptor Antagonist 2 is a potent and orally active antagonist of Gastrin/CCK-B (IC50: 0.43 nM). It also inhibits gastrin/CCK-A activity (IC50: 1.82 μM).		Others
T13261	CCK-B Receptor Antagonist 1		Others
	CCK-B Receptor Antagonist 1 is a cholecystokinin B (CCK-B) receptor agonist and has the potential of reducing the secretion of gastric acid.		Others
TP1197	Sincalide	SQ19844,CCK-8,Cholecystokinin octapeptide	Others
	Sincalide (CCK-8) is a cholecystokinetic drug administered by injection to aid in diagnosing disorders of the gallbladder and pancreas. It is the 8-amino acid C-terminal fragment of cholecystokinin.		Others
T1052	Proglumide		cholecystokinin
	Proglumide (Binoside) is a cholecystokinin antagonist, which blocks both the CCKA and CCKB subtypes. Proglumide is a drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is...		cholecystokinin
T16906	Sograzepide	YM-220,Netazepide,YF 476	Others
	Sograzepide is an effective and highly selective Gastrin/CCK-B antagonist (IC50: 0.1 nM), has an inhibitory effect on Gastrin/CCK-A activity (IC50: 502 nM). Sograzepide replaces the specific binding of [125I]CCK-8 to the...		Others
T25139	BC 197	Boc-asp-tyr(SO3H)-ahx-lys-trp-ahx-asp-phe-NH2,BC197,BC-197
	BC 197 is a selective CCK-B agonist.
T22666	CI-988	CI 988	Others
	CCK2 (CCK-B) receptor antagonist		Others
T26197	Snf 8815	Snf8815,Snf-8815,28-Mephe-31-N-meile-cck (26-33)
	Snf 8815 is an antagonist of cholecystokinin-B (CCK-B).
T27014	CI-1015	CI1015,CI 1015,PD 144598
	CI-1015 is a CCK-B receptor antagonist with oral activity.
T27774	L-740093	L 740093
	L-740093 is a specific antagonist of CCK-B receptor.
T17274	YM022		CCR
	YM022 is a highly effective and selective gastrin/cholecystokinin (CCK)-B receptor antagonist. YM022 can inhibit gastrin-induced gastric acid secretion and histidine decarboxylase activation in vivo. YM022 shows the Ki v...		CCR
T26482	A-57696
	A-57696 is a cholecystokinin antagonist with selective for cortical CCK-B receptors (IC50 = 25 nM).
T23946	DA-3934	UNII-J353803KRG
	DA-3934 has a high affinity for gastrin/CCK-B receptors and high selectivity over CCK-A receptors. DA-3934 and its methyl ester derivative inhibited pentagastrin-induced gastric acid secretion in rats in a dose-dependent...
T28331	PD 136450	Cam1189,PD136450,Cam-1189,PD-136450,Cam 1189
	Cholecystokinin type B receptor antagonist PD-136,450 is a partial secretory agonist in the stomach and a full agonist in the pancreas of the rat. Gastrin (cholecystokinin type B (CCK-B)) receptor antagonists may help to...
T27772	L-736380	L-736,380,L 736380,L736,380,L 736,380
	L-736380 is a CCK-B receptor antagonist. L-736,380 dose-dependently inhibited gastric acid secretion in anesthetized rats (ID(50), 0.064 mg/kg) and ex vivo binding of [(125)I]CCK-8S in BKTO mice brain membranes (ED(50), ...
T62039	L-365260 hemihydrate
	L-365260 hemihydrate is a selective, orally active non-peptide gastrin and brain cholecystokinin receptor (CCK-B) antagonist, demonstrating competitive interaction with guinea pig stomach gastrin and brain CCK receptors ...
T12544	Proglumide hemicalcium		Others
	Proglumide hemicalcium is a antagonist of nonpeptide and orally active cholecystokinin (CCK)-A/B receptors, has antiepileptic and antioxidant activities.		Others
T8761	[Leu15]-Gastrin I human	Amino Acid Sequence Glp-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Leu-Asp-Phe-NH2	Others
	[Leu15]-Gastrin I human (Amino Acid Sequence Glp-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Leu-Asp-Phe-NH2) encodes for the protein [Leu15]-Gastrin I in human. In human chromosome, the gene GAST is localized on...		Others