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Search Results for " cbf "

6

Compounds

Cat No. Product Name Synonyms Targets
T2671 Regadenoson CVT-3146,Lexiscan Adenosine Receptor
Regadenoson (CVT-3146) is an adenosine derivative and selective A2A adenosine receptor agonist with coronary vasodilating activity. Upon administration, regadenoson selectively binds to and activates the A2A adenosine re...
T4687 Ro5-3335 CBFβ-Runx1 inhibitor II,Ro 5-3335 DNA/RNA Synthesis
Ro5-3335 (CBFβ-Runx1 inhibitor II) is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins (IC50 = 1.1 μM). Ro5-3335 represses RUNX1/CBFβ-dependent transactivation ...
T22195 CBFβ Inhibitor 5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine DNA/RNA Synthesis
CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1.
T33272 Mefenidil McN-2378,McN 2378 Others
Mefenidil (McN-2378), a selective cerebral vasodilator, was shown to increase CBF in healthy brains without stimulating O2 uptake in a dog anesthesia model.
T24170 Iodoantipyrine Jodantipyrine,EINECS 204-966-6,Arthripur,Iodophenazone Others
Iodoantipyrine (Arthripur) is a commonly-used indicator and is used to evaluate in rats by measuring torcular venous efflux after systemic injection of the indicator under conditions of normal and high CBF.
T62920 HDAC-IN-38
HDAC-IN-38 is a potent inhibitor of HDAC. HDAC-IN-38 has similar micromolar inhibitory effects on HDAC1, 2, 3, 5, 6 and 8, and also increases histone acetylation levels (H3K14 or H4K5). HDAC-IN-38 increases cerebral bloo...
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