carm1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10682L	CARM1-IN-1	CARM1-IN-7G	Histone Methyltransferase
	CARM1-IN-1 (CARM1-IN-7G) is a selective inhibitor of CARM1 with IC50 of 8.6 μM. CARM1-IN-1 shows weak activity against PRMT1 and SET7 with IC50 > 600 μM.		Histone Methyltransferase
T79007	CARM1-IN-3		Histone Methyltransferase
	CARM1-IN-3 (compound 17b) is a potent, selective inhibitor of co-activator associated arginine methyltransferase (CARM1), exhibiting IC50 values of 0.07 µM for CARM1 and greater than 25 µM for CARM3 [1].		Histone Methyltransferase
T79741	CARM1 degrader-1		Histone Methyltransferase
	PROTAC CARM1 degrader-1 (compound 3b) serves as a highly potent degrader (DC50=8.1 nM) of the co-activator associated arginine methyltransferase (CARM1). This compound facilitates the degradation of CARM1 via the VHL-pro...		Histone Methyltransferase
T79742	CARM1 degrader-2		Histone Methyltransferase
	PROTAC CARM1 degrader-2 (compound 3e), with a DC50 value of 8.8 nM, is a VHL- and proteasome-dependent degrader of co-activator associated argininemethyltransferase (CARM1). It not only promotes the degradation of CARM1 ...		Histone Methyltransferase
T63180	CARM1-IN-3 dihydrochloride
	CARM1-IN-3 dihydrochloride (compound 17b) CARM1-IN-3 dihydrochloride (compound 17b) is a potent, selective coactivator-associated arginine methyltransferase (CARM1) inhibitor that acts on CARM1 (IC50: 0.07 μM) and CARM3 ...
T64186	CARM1-IN-1 hydrochloride
	CARM1-IN-1 hydrochloride is a potent and selective inhibitor of CARM1 (IC50: 8.6 μM) with low inhibition of PRMT1 and SET7.
T28996	TP-064	TP 064	Histone Methyltransferase
	TP-064 is a potent and selective PRMT4 inhibitor. TP-064 includes inhibition of PRMT4 with IC50 < 10nM for methylation of H3 (1-25) and greater than 100-fold selectivity over other histone methyltransferases and non-epig...		Histone Methyltransferase
T5605	EZM 2302	GSK3359088	Histone Methyltransferase
	EZM 2302 (GSK3359088) is a selective, and orally available arginine methyltransferase CARM1 inhibitor (IC50: 6 nM).		Histone Methyltransferase
T7089	SGC2085		Histone Methyltransferase
	SGC2085 is an effective and selective coactivator-associated arginine methyltransferase 1 (CARM1) inhibitor (IC50: 50 nM).		Histone Methyltransferase
T4013	SGC2085 HCl		Histone Methyltransferase
	SGC2085 is a potent and selective coactivator associated arginine methyltransferase 1 (CARM1) Inhibitor with an IC50 of 50 nM and more than undred-fold selectivity over other PRMTs. CARM1 is an important positive modulat...		Histone Methyltransferase
T10967	DC_C66		Others
	DC_C66 DC_C66 has good selectivity for CARM1, PRMT1 (IC50 = 21μM), PRMT6 (IC50 = 47μM) and PRMT5. It is a cell-permeable, selective co-activator related arginine methyltransferase 1 (CARM1) inhibitor with IC50 of 1.8 μM.		Others
T24037	EPZ-025654 HCl	EPZ 025654,EPZ-025654,GSK35336023,EPZ025654,GSK-35336023,GSK 35336023
	EPZ-025654 is an effective and selective inhibitor of arginine methyltransferase CARM1.
T72013	Epigenetic Multiple Ligand
	Epigenetic Multiple Ligand is a cell-permeable inhibitor of substrate processing by several chromatin-associated enzymes, including SIRT1/2, H3/SET7, H3/p300/CBP, H4/RmtA, PABP1/CARM1, and H4/PRMT1. It acts by inducing e...
TP2041	C 21
	Selective protein arginine methyltransferase 1 (PRMT1) inhibitor (IC50 = 1.8 μM). Exhibits five-fold selectivity for PRMT1 over PRMT6 and >250-fold selectivity over PRMT3 and CARM1.
T11338	Furamidine	DB75,NSC 305831	Others
	Furamidine is also a selective and cell-permeable protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC50 of 9.4 μM. Furamidine is selective for PRMT1 over PRMT5, PRMT6, and PRMT4 (CARM1) (IC50s of 166 μM, 28...		Others