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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6410 | Bexarotene | Ro 26-4455,Targretin,LGD1069 | Retinoid Receptor , Autophagy |
Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL). | |||
T10528 | Bexarotene D4 | LGD1069 D4 | Others |
Bexarotene D4 is a deuterium-labeled Bexarotene (LGD1069). Bexarotene is a selective RXR agonist used in the treatment of cutaneous T-cell lymphoma. | |||
T11303 | Fluorobexarotene | Retinoid Receptor | |
Fluorobexarotene possesses an apparent RXR binding affinity that is 75% greater than Bexarotene. Fluorobexarotene is a potent retinoid-X-receptor (RXR) agonist, with a Ki value of 12 nM and an EC50 value of 43 nM for RX... | |||
T33766 | OAB-14 | OAB 14,OAB14 | |
OAB-14 is a Bexarotene derivative that improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice. OAB-14 effectively ameliorates the dysfunction of the e... |