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Search Results for " brpf2 "

8

Compounds

Cat No. Product Name Synonyms Targets
T1972 GSK-5959 Epigenetic Reader Domain
GSK-5959 is an effective, specific and cell permeable BRPF1 bromodomain inhibitor (IC50: ~80 nM). The selectivity of GSK-5959 for BRPF1 is >100-fold over a panel of 35 other bromodomains, including BRPF2/3 and BET family...
T2127 OF-1 Epigenetic Reader Domain
OF-1 is a potent inhibitor of BRPF1B and BRPF2 bromodomain.
TQ0083 NI-57 Epigenetic Reader Domain
NI-57 is an inhibitor of proteins of bromodomain and plant homeodomain finger-containing (BRPF) family, with IC50s of 3.1, 46 and 140 nM for BRPF1, BRPF2 (BRD1) and BRPF3, respectively.
T14502 BAY-299 BAY299,BAY 299 Epigenetic Reader Domain , Carboxypeptidase
BAY-299 is an effecitve inhibitor of the bromodomain and PHD finger family member BRPF2 and the TATA box binding protein-associated factors TAF1 and TAF1L with IC50s of 67 nM, 8 nM, and 106 nM, respectively.
T13715L GSK9311 Epigenetic Reader Domain
GSK9311 inhibits BRPF bromodomain (pIC50: 6.0 and 4.3 for BRPF1 and BRPF2, respectively). GSK9311 is a less active analog of GSK6853. It can be used as a negative control.
T13715 GSK9311 hydrochloride Epigenetic Reader Domain
GSK9311 hydrochloride, a less active analog of GSK6853, can be used as a negative control. GSK9311 hydrochloride inhibits BRPF bromodomain (pIC50s: 6.0 and 4.3 for BRPF1 and BRPF2).
T1973 PFI-4 PFI4 Epigenetic Reader Domain
PFI-4 is a potent and selective and cell-permeable BRPF1 bromodomain inhibitor.
T16321 NI-42 Epigenetic Reader Domain
NI-42 is a structurally orthogonal chemical probe for the BRPFs and is biased. It effective inhibitor of the BRD of the BRPFs (IC50s of BRPF1/2/3=7.9/48/260 nM; Kds of BRPF1/2/3=40/210/940 nM). It also has excellent sele...
TargetMol