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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T18363 | Monoethyl pimelate | Others , PROTAC Linker | |
Monoethyl pimelate is a <b >PROTAC linker, which refers to the alkyl/ether composition. Monoethyl pimelate can be used in the synthesis of (S,R,S)-AHPC-Me-C7 ester, a specific BCL-XL PROTAC degrader[1]. | |||
T18671 | (S,R,S)-AHPC-Me-C7 ester | Others | |
(S,R,S)-AHPC-Me-C7 ester is a E3 ligase ligand-linker conjugate used to synthesise BCL-XL PROTAC degraders[1]. | |||
T78873 | CTL-12 | ||
CTL-12, a fatty acid synthase (FASN) inhibitor (IC50: 2.5 μM), induces apoptosis and disrupts the cell cycle at the Sub-G1/S phase. It upregulates caspase-9 and the apoptosis marker Bax, while downregulating the anti-apo... | |||
T78872 | CTL-06 | ||
CTL-06, a Fatty Acid Synthase (FASN) inhibitor with an IC50 of 3 μM, induces apoptosis, while CTL-12 impedes cell cycle progression in the Sub-G1/S phase and modulates apoptotic and anti-apoptotic markers by upregulating... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02431 | BCL-XL Protein, Human, Recombinant (His) | Human | E. coli |
BCL-XL Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 25.2 kDa and the accession number is A0A0S2Z3C5. |