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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T35868 | BCAT-IN-2 | Others | |
BCAT-IN-2 is an orally active and selective inhibitor of mitochondrial branched-chain aminotransferase (BCATm), inhibits BCATm and BCATc, and is used in obesity and dyslipidemia. | |||
T77522 | BCAT-IN-4 | Others | |
BCAT-IN-4 is a potent BCAT inhibitor with an IC50 value of 2.35 μM for hBCATc. BCAT-IN-4 has anticancer activity and can be used to study pancreatic ductal adenocarcinoma. | |||
T40218 | BCAT-IN-1 | ||
BCAT-IN-1 is a potent, selective and orally active inhibitor of BCATm, with a pIC 50 of 7.3. BCAT-IN-1 is 100-fold more selective for BCATm than BCATc ( pIC 50 =5.4). BCAT-IN-1 can be used for the research of metabolic d... | |||
T22043 | BCATc Inhibitor 2 | Others | |
BCATc Inhibitor 2 exhibited an IC50 of 0.8 microM in the hBCATc assays; it is an active and selective inhibitor. BCATc Inhibitor 2 also blocked calcium influx into neuronal cells following inhibition of glutamate uptake,... | |||
T5198 | Bobcat339 | Bobcat339 hydrochloride | DNA Methyltransferase |
Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a. | |||
T61012 | Bobcat339 hydrochloride | ||
Bobcat339 hydrochloride can be used in the field of epigenetics and as a starting point for new therapeutics targeting DNA methylation and gene transcription. Bobcat339 hydrochloride is a potent and selective cytosine-ba... |