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Search Results for " apoe4 "

Targets

3

Compounds

4

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T16518 PH-002 Others
PH-002, an inhibitor targeting the intramolecular domain interaction of apolipoprotein (apo) E4 in neuronal cells, additionally enhances mitochondrial motility and promotes neurite outgrowth, thereby countering related i...
T15265 EZ-482 Others
EZ-482 is a novel ligand of apolipoprotein (apoE). EZ-482 binds to apoE4 by a unique N-terminal allosteric effect and it also binds to sites on apoE in the C-terminal domain (Kds: 5-10 μM for apoE3 and apoE4).
T36521 Alaproclate (hydrochloride)
Alaproclate is a selective serotonin reuptake inhibitor (SSRI).1,2 It inhibits depletion of serotonin (5-HT) induced by 4-methyl-α-ethyl-m-tyramine in rat cerebral cortex, hippocampus, hypothalamus, and striatum (EC50s =...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPK-00589 Apolipoprotein E/APOE4 Protein, Human, Recombinant (His) Human HEK293
Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury...
TMPK-00588 Apolipoprotein E/APOE4 Protein, Human, Recombinant (hFc) Human HEK293
Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury...
TMPY-05297 Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx) Human E. coli
Apolipoprotein E (ApoE) is a 34.2 kDa glycosylated protein with 299 amino acid residues. There are three isoforms in human (apoE2, apoE3, and apoE4) due to different amino acid residues at positions 112 and 158. ApoE is ...
TMPY-05528 Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated Human E. coli
Apolipoprotein E (ApoE) is a 34.2 kDa glycosylated protein with 299 amino acid residues. There are three isoforms in human (apoE2, apoE3, and apoE4) due to different amino acid residues at positions 112 and 158. ApoE is ...
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