Powder: -20°C for 3 years | In solvent: -80°C for 1 year
EZ-482 is a novel ligand of apolipoprotein (apoE). EZ-482 binds to apoE4 by a unique N-terminal allosteric effect and it also binds to sites on apoE in the C-terminal domain (Kds: 5-10 μM for apoE3 and apoE4).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 116.00 | |
50 mg | 6-8 weeks | $ 789.00 | |
100 mg | 6-8 weeks | $ 1,320.00 |
Description | EZ-482 is a novel ligand of apolipoprotein (apoE). EZ-482 binds to apoE4 by a unique N-terminal allosteric effect and it also binds to sites on apoE in the C-terminal domain (Kds: 5-10 μM for apoE3 and apoE4). |
Targets&IC50 | ApoE3/ApoE4:(kd)5-10 μM |
In vitro | EZ-482 (0.5, 1, 5, 10 μM; 1 hour) blocks heparin-binding in a concentration-dependent manner. EZ-482 binds to sites on apoE in the C-terminal domain encompassing residues 229-243 and 258-265. |
Molecular Weight | 498.94 |
Formula | C23H19ClN4O5S |
CAS No. | 1016456-76-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
EZ-482 1016456-76-0 Others EZ 482 EZ482 inhibitor inhibit