3
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2339 | Apalutamide | ARN-509 | Androgen Receptor , GABA Receptor |
Apalutamide (ARN-509) is a small molecule and androgen receptor (AR) antagonist with potential antineoplastic activity. | |||
T12146 | N-Desmethyl-Apalutamide | N-Desmethyl Apalutamide | P450 , Androgen Receptor |
N-Desmethyl-Apalutamide is a less potent antagonist of the androgen receptor, is an active Apalutamide metabolite. | |||
T38725 | Apalutamide-COOH | ||
Apalutamide-COOH is a metabolite derived from Apalutamide, which acts as a highly potent and competitive antagonist of the androgen receptor (AR). It effectively binds to the AR with an IC50 value of 16 nM. |