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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP1232L | Amylin, amide, rat acetate(124447-81-0,free base) | Amylin Receptor | |
Amylin, amide, rat acetate is a potent and high affinity ligand of AMY1 and AMY3 receptors and variably of AMY2 receptors. | |||
TP1232 | Amylin, amide, rat | Amylin (rat) | |
Amylin is a peptide that displays 50% homology with calcitonin gene-related peptide (CGRP), Amylin is colocalized with somatostatin in endocrine cells of the gastric fundus. In isolated mouse stomach, amylin caused a con... | |||
TP1233 | Amylin (8-37), rat | Amylin (8-37) (mouse, rat) | |
Amylin (8-37), rat is a truncated analog of native Amylin that selectively inhibits insulin-related glucose uptake and glycogen deposition in muscle tissue. Amylin is also known as islet amyloid precursor peptide (IAPP) ... | |||
T35627 | Amylin (human) (trifluoroacetate salt) | ||
Amylin is a 37-residue peptide hormone secreted from pancreatic β-cells that reduces food intake, decreases glucagon secretion, slows gastric emptying, and increases satiety. It binds to amylin receptors with IC50 values... | |||
T38764 | Amylin (8-37), human | ||
Amylin (8-37), human, derived from human Amylin, possesses direct vasodilator effects in isolated mesenteric resistance arteries of rats. Human Amylin is a small pancreatic β-cell hormone that forms aggregates in the abs... | |||
TP1519 | Amylin (IAPP), feline | ||
Amylin (IAPP), feline is the peptide subunit of amyloid found in pancreatic islets of type 2 diabetic patients and in insulinomas. | |||
TP1183 | Amylin, amide, human | DAP amide, human | |
Amylin, a 37-amino acid polypeptide that is structurally related to calcitonin, is secreted from the B cells of the pancreas. Amylin has anoretic effects in rats. Amylin may be responsible for the etiology of insulin res... | |||
T75787 | Amylin, amide, human TFA | ||
Amylin, amide, human TFA, a 37-amino acid polypeptide, functions as a pancreatic hormone that is cosecreted with insulin, playing distinct roles in metabolism and glucose homeostasis. It regulates blood sugar by inhibiti... | |||
T76645 | Acetyl-Amylin (8-37) (human) | ||
Acetyl-Amylin (8-37) (human) is a specific amylin antagonist [1] . | |||
T76478 | Amylin (8-37) (human) | ||
Amylin (8-37) (human) (hIAPP (8-37)) represents the 8-37 fragment of human islet amyloid polypeptide (IAPP). This assembly exhibits a duplex folding with a hairpin structure [1]. | |||
T76480 | Amylin (1-37) (human) | ||
Amylin (1-37) (human) (hIAPP (1-37)), a peptide hormone found in pancreatic beta-cell secretory granules, features an amidated C-terminus and a disulfide bond between cysteine residues 2 and 7 [1]. | |||
T76028 | Amylin (IAPP), feline TFA | ||
Amylin (IAPP), feline TFA, a 37-amino acid polypeptide derived from felines, stands as a principal secretion product of the pancreatic islets' β-cells. This regulatory peptide notably inhibits the secretion of insulin an... | |||
T81678 | NF(N-Me)GA(N-Me)IL | Amylin (22-27) [NMeG24, NMeI26], human (IAPP) | |
NF(N-Me)GA(N-Me)IL is a biologically active peptide, representing a modified segment (amino acids 22 to 27) of the human islet amyloid polypeptide (hIAPP) sequence NFGAIL. This modification includes N-methylations at G24... | |||
T21581L | AC 187 Acetate | AC 187 Acetate (151804-77-2 Free base) | Amylin Receptor |
AC 187 Acetate is a potent antagonist of amylin receptor .AC 187 shows more selective for amylin receptor than calcitonin and CGRP receptors. | |||
TP2135L | CAC 253 acetate | cAC 253 acetate (TP2135 Free base) | Amylin Receptor |
cAC 253 acetate (TP2135 Free base) is an amylin antagonist. cAC 253 acetate inhibits 125I-adrenomedullin binding, with an IC50 of 25 nM. | |||
TP2320 | Pramlintide acetate(151126-32-8 free base) | Others | |
Pramlintide acetate is a polypeptide analogue of human amylin. It serves as an antidiabetic agent and exhibits antineoplastic activity in colorectal cancer. | |||
T38998 | Pramlintide | ||
Pramlintide, a polypeptide analog of human amylin, is an antidiabetic agent with antineoplastic properties in colorectal cancer. | |||
T75934 | AC 187 TFA | ||
AC 187 TFA, a potent and orally active amylin receptor antagonist, exhibits an IC50 of 0.48 nM and a Ki of 0.275 nM. It demonstrates greater selectivity for the amylin receptor over calcitonin and CGRP receptors and has ... | |||
TP1257 | Adrenomedullin (AM) (22-52), human | 22-52-Adrenomedullin (human) | |
Adrenomedullin (ADM) is a 52-aa hypotensive peptide. Adrenomedullin (ADM) has structural similarity with amylin. | |||
T36911 | Pramlintide (acetate hydrate) | ||
Pramlintide is a non-amyloidogenic analog of the antidiabetic peptide hormone amylin that contains proline residues substituted at positions 25, 28, and 29. It stimulates cAMP production in HEK293 cells expressing human ... |