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Compounds

Cat No. Product Name Synonyms Targets
TP1232L Amylin, amide, rat acetate(124447-81-0,free base) Amylin Receptor
Amylin, amide, rat acetate is a potent and high affinity ligand of AMY1 and AMY3 receptors and variably of AMY2 receptors.
TP1232 Amylin, amide, rat Amylin (rat)
Amylin is a peptide that displays 50% homology with calcitonin gene-related peptide (CGRP), Amylin is colocalized with somatostatin in endocrine cells of the gastric fundus. In isolated mouse stomach, amylin caused a con...
TP1233 Amylin (8-37), rat Amylin (8-37) (mouse, rat)
Amylin (8-37), rat is a truncated analog of native Amylin that selectively inhibits insulin-related glucose uptake and glycogen deposition in muscle tissue. Amylin is also known as islet amyloid precursor peptide (IAPP) ...
T35627 Amylin (human) (trifluoroacetate salt)
Amylin is a 37-residue peptide hormone secreted from pancreatic β-cells that reduces food intake, decreases glucagon secretion, slows gastric emptying, and increases satiety. It binds to amylin receptors with IC50 values...
T38764 Amylin (8-37), human
Amylin (8-37), human, derived from human Amylin, possesses direct vasodilator effects in isolated mesenteric resistance arteries of rats. Human Amylin is a small pancreatic β-cell hormone that forms aggregates in the abs...
TP1519 Amylin (IAPP), feline
Amylin (IAPP), feline is the peptide subunit of amyloid found in pancreatic islets of type 2 diabetic patients and in insulinomas.
TP1183 Amylin, amide, human DAP amide, human
Amylin, a 37-amino acid polypeptide that is structurally related to calcitonin, is secreted from the B cells of the pancreas. Amylin has anoretic effects in rats. Amylin may be responsible for the etiology of insulin res...
T75787 Amylin, amide, human TFA
Amylin, amide, human TFA, a 37-amino acid polypeptide, functions as a pancreatic hormone that is cosecreted with insulin, playing distinct roles in metabolism and glucose homeostasis. It regulates blood sugar by inhibiti...
T76645 Acetyl-Amylin (8-37) (human)
Acetyl-Amylin (8-37) (human) is a specific amylin antagonist [1] .
T76478 Amylin (8-37) (human)
Amylin (8-37) (human) (hIAPP (8-37)) represents the 8-37 fragment of human islet amyloid polypeptide (IAPP). This assembly exhibits a duplex folding with a hairpin structure [1].
T76480 Amylin (1-37) (human)
Amylin (1-37) (human) (hIAPP (1-37)), a peptide hormone found in pancreatic beta-cell secretory granules, features an amidated C-terminus and a disulfide bond between cysteine residues 2 and 7 [1].
T76028 Amylin (IAPP), feline TFA
Amylin (IAPP), feline TFA, a 37-amino acid polypeptide derived from felines, stands as a principal secretion product of the pancreatic islets' β-cells. This regulatory peptide notably inhibits the secretion of insulin an...
T81678 NF(N-Me)GA(N-Me)IL Amylin (22-27) [NMeG24, NMeI26], human (IAPP)
NF(N-Me)GA(N-Me)IL is a biologically active peptide, representing a modified segment (amino acids 22 to 27) of the human islet amyloid polypeptide (hIAPP) sequence NFGAIL. This modification includes N-methylations at G24...
T21581L AC 187 Acetate AC 187 Acetate (151804-77-2 Free base) Amylin Receptor
AC 187 Acetate is a potent antagonist of amylin receptor .AC 187 shows more selective for amylin receptor than calcitonin and CGRP receptors.
TP2135L CAC 253 acetate cAC 253 acetate (TP2135 Free base) Amylin Receptor
cAC 253 acetate (TP2135 Free base) is an amylin antagonist. cAC 253 acetate inhibits 125I-adrenomedullin binding, with an IC50 of 25 nM.
TP2320 Pramlintide acetate(151126-32-8 free base) Others
Pramlintide acetate is a polypeptide analogue of human amylin. It serves as an antidiabetic agent and exhibits antineoplastic activity in colorectal cancer.
T38998 Pramlintide
Pramlintide, a polypeptide analog of human amylin, is an antidiabetic agent with antineoplastic properties in colorectal cancer.
T75934 AC 187 TFA
AC 187 TFA, a potent and orally active amylin receptor antagonist, exhibits an IC50 of 0.48 nM and a Ki of 0.275 nM. It demonstrates greater selectivity for the amylin receptor over calcitonin and CGRP receptors and has ...
TP1257 Adrenomedullin (AM) (22-52), human 22-52-Adrenomedullin (human)
Adrenomedullin (ADM) is a 52-aa hypotensive peptide. Adrenomedullin (ADM) has structural similarity with amylin.
T36911 Pramlintide (acetate hydrate)
Pramlintide is a non-amyloidogenic analog of the antidiabetic peptide hormone amylin that contains proline residues substituted at positions 25, 28, and 29. It stimulates cAMP production in HEK293 cells expressing human ...
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