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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1445 | Agomelatine | Thymanax,S-20098,Valdoxan | Melatonin Receptor , 5-HT Receptor |
Agomelatine (Valdoxan) is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. | |||
T60523 | Agomelatine hydrochloride | S-20098 hydrochloride | MT Receptor |
Agomelatine hydrochloride (S-20098 hydrochloride) (S-20098 hydrochloride) is a specific MT1 and MT2 receptor agonist with Ki of 0.1 nM for CHO-hMT1, 0.06 nM for HEK-hMT1, 0.12 nM for CHO-hMT2, and 0.27 nM for HEK-hMT2, r... | |||
T10266 | Agomelatine-d6 | Agomelatine D6,S-20098 D6 | Others |
Agomelatine D6 (S-20098 D6) is a deuterium-labeled Agomelatine. Agomelatine is a specific agonist of MT1 and MT2 receptors. | |||
T10113 | 3-Hydroxy agomelatine D3 | 5-HT Receptor | |
3-Hydroxy agomelatine D3 is a deuterium labeled 3-Hydroxy agomelatine. 3-Hydroxy agomelatine is an Agomelatine metabolite and a 5-HT2C receptor antagonist (IC50: 3.2 μM; Ki: 1.8 μM). | |||
T10114 | 3-Hydroxy agomelatine | 5-HT Receptor | |
3-Hydroxy agomelatine is an Agomelatine metabolite and a 5-HT2C receptor antagonist (IC50: 3.2 μM; Ki: 1.8 μM). | |||
T10193 | 7-Desmethyl-agomelatine | Others | |
7-Desmethyl-agomelatine is a metabolite of Agomelatine and has less activity than Agomelatine. Agomelatine is a melatonergic (MT1 and MT2) agonist and 5-HT2C antagonist. | |||
T19162 | 7-Desmethyl-agomelatine D3 | Others | |
7-Desmethyl-agomelatine D3 is a deuterium labeled 7-Desmethyl-agomelatine. 7-Desmethyl-agomelatine is a metabolite of Agomelatine. | |||
T10267 | Agomelatine (L(+)-Tartaric acid) | S-20098 L(+)-Tartaric acid | 5-HT Receptor |
Agomelatine (S-20098) L(+)-Tartaric acid is a specific agonist of MT1 and MT2 receptors (Kis: 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2). It also is a selective 5-HT2C receptor antagonis... | |||
T10192 | 7-Desmethyl-3-hydroxyagomelatine | 3-Hydroxy-7-desmethyl agomelatine | 5-HT Receptor |
7-Desmethyl-3-hydroxyagomelatine is a metabolite of Agomelatine and has less activity than Agomelatine. Agomelatine is a melatonergic (MT1 and MT2) agonist and 5-HT2C antagonist. | |||
T9898 | 2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride | Others | |
2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride is the impurity of Agomelatine, an antidepressant. | |||
T9896 | 7-Methoxy-1-naphthylacetonitrile | Others | |
7-Methoxy-1-naphthylacetonitrile is one of the impurities of agomelatine, an antidepressant. |