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Search Results for " ard-266 "

6

Compounds

Cat No. Product Name Synonyms Targets
T13552 ARD-266 Others
ARD-266 is a highly potent and VHL E3 ligase-based androgen receptor (AR) PROTAC degrader. ARD-266 effectively induces the degradation of AR protein in AR-positive LNCaP, VCaP, and 22Rv1 prostate cancer cell lines (DC50s...
T10359 AR antagonist 1 Androgen Receptor , Ligand for E3 Ligase , Ligands for Target Protein for PROTAC
AR antagonist 1 is a potent antagonist of the androgen receptor. It binds to E3 ligase ligands with weak binding affinities to VHL protein in the synthesis of PROTAC ARD-266.
T18873 VHL Ligand-Linker Conjugates 17 Others
VHL Ligand-Linker Conjugates 17 are chemical compounds that consist of a VHL ligand specialized for the E3 ubiquitin ligase, as well as a PROTAC linker. These conjugates are utilized in the synthesis of various PROTACs, ...
T18545 Pip-alkyne-Ph-COOCH3 Others
Pip-alkyne-Ph-COOCH3 is an alkyl-chain based PROTAC linker utilized for the synthesis of PROTAC ARD-266[1].
T13958 VHL Ligand 8 Others
VHL Ligand 8, a VHL ligand essential for synthesizing ARD-266, acts as a highly potent VHL E3 ligase-based androgen receptor (AR) PROTAC degrader. It efficiently facilitates the degradation of AR protein in AR-positive p...
T17689 Boc-Pip-alkyne-Ph-COOH Others
Boc-Pip-alkyne-Ph-COOH, a PROTAC linker characterized by its alkyl/ether composition, plays a crucial role in synthesizing PROTACs including ARD-266. This compound demonstrates significant efficacy in promoting the degra...
TargetMol