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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8969 | API-1 | NSC177223 | Akt |
API-1 (NSC-177223) is a potent inhibitor of Akt. It induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis . | |||
T16538 | PIN1 inhibitor API-1 | Others | |
PIN1 inhibitor API-1 is a specific Pin1 inhibitor (IC50: 72.3 nM). PIN1 inhibitor API-1 retains the active conformation of pXPO5 and restores the ability of pXPO5 to transport pre-miRNAs from the nucleus to cytoplasm, th... | |||
T6009 | TAPI1 | TAPI 1,TAPI,TAPI-1 | MMP |
TAPI1 (TAPI) , an ADAM17/TACE inhibitor, inhibits shedding of cytokine receptors. | |||
T80402 | Api137 | ||
Api137 is an antimicrobial peptide that disrupts bacterial growth by blocking translation processes. Specifically, it inhibits protein synthesis through the entrapment of release factors on the 70S ribosome after the hyd... |