aldos — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T14175	Aldose reductase-IN-1	AT-001,Caficrestat	Others , Reductase
	Aldose reductase-IN-1 (AT-001) is a aldose reductase inhibitor (IC50: 28.9 pM).		Others , Reductase
T75390	Aldose 1-epimerase
	Aldose 1-epimerase (mutarotases), an essential enzyme for carbohydrate metabolism, facilitates the interconversion between α- and β-anomers of hexose sugars, including glucose and galactose. This enzyme plays a vital rol...
T60601	Aldose reductase-IN-4
	Aldose reductase-IN-4 (compund IIc) is an inhibitor of aldose reductase with IC50s of 11.70 μM and 0.98 μM for ALR1 and ALR2, respectively [1].
T61957	Aldose reductase-IN-3
	Aldose reductase-IN-3 (Compound 5) is an effective and moderately selective aldose reductase (AR) inhibitor (IC50=3.99 μ M). Aldose reductase is a molecular target involved in various inflammatory diseases (including sep...
T62951	Aldose reductase-IN-2
	Aldose reductase-IN-2 (Compound 5f) is a potent inhibitor of aldose reductase (AR) with antioxidant properties. aldose reductase-IN-2 is a promising anti-diabetic complication drug.
T29852	Aldosterone-3-(O-carboxymethyl)oximino-(2-iodohistamine)
	Aldosterone-3-(O-carboxymethyl)oximino-(2-iodohistamine) is a biochemical.
T19185	Aldosterone-d8	Aldosterone D8	Others
	Aldosterone D8, a deuterium-labeled variant of Aldosterone produced in the adrenal zona glomerulosa, regulates blood pressure.		Others
T61555	Aldose reductase-IN-6
	Aldose reductase-IN-6 (Compound 3) is a competitive inhibitor of aldose reductase (AR), possessing an IC50 of 3.164 μM and a Ki of 0.018 μM. Notably, Aldose reductase-IN-6 demonstrates no cytotoxicity toward normal cells...
T36381	Aldosterone 21-sulfate (sodium salt)
	Aldosterone 21-sulfate is a metabolite of the steroid hormone aldosterone .1It reduces the sodium-to-potassium ratio in rat urine when administered at doses ranging from 10 to 100 μg, indicating mineralocorticoid activit...
T60897	Aldose reductase-IN-5
	Aldose reductase-IN-5 is an inhibitor of aldose reductase (ALR2) that enhances the combination of inhibitory excitability and antioxidant capacity, thereby delaying the diabetes complications progress.

Compounds

Aldose reductase-IN-1

T14175

Synonym: AT-001,Caficrestat

Target: Others, Reductase

Aldose reductase-IN-4

T60601

Synonym:

Target:

Aldose reductase-IN-3

T61957

Synonym:

Target:

Aldose reductase-IN-2

T62951

Synonym:

Target:

Aldosterone-3-(O-carboxymethyl)oximino-(2-iodohistamine)

Synonym: Aldosterone D8

Target: Others

Aldose reductase-IN-6

T61555

Synonym:

Target:

Aldosterone 21-sulfate (sodium salt)

T36381

Synonym:

Target:

Aldose reductase-IN-5

T60897

Synonym:

Target:

Cat No.	Product Name	Targets
TN7214	Galdosol	Others
	Galdosol is a natural product found in Perovskia abrotanoides.	Others
T19186	Aldosterone	Others
	Aldosterone is the primary mineralocorticoid. Aldosterone is synthesized and secreted in response to renin-angiotensin system activation or high dietary potassium by the zona glomerulosa of the adrenal cortex.	Others
TN5276	(Z)-Aldosecologanin (Centauroside)	Others
	(Z)-Aldosecologanin is a natural product from Lonicera japonica.	Others
TN3908	(E)-Aldosecologanin	Others
	(E)-Aldosecologanin is a natural product from Lonicera japonica.	Others