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Search Results for " akr1c2 "

Targets

4

Compounds

1

Natural Products

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T38684 AKR1C3-IN-4 AKR1C3-IN-4 NADPH
AKR1C3-IN-4 is a potent and selective inhibitor of aldo-keto reductase 1C3 (AKR1C3) with an IC50 of 0.56 μM. AKR1C3-IN-4 has the potential for castrate resistant prostate cancer (CRPC) research.
T61790 AKR1C3-IN-6
AKR1C3-IN-6 (Compound 1) is a powerful and specific inhibitor of AKR1C3, with IC50 values of 0.31 μM and 73.23 μM against AKR1C3 and AKR1C2, respectively. It demonstrates significant antitumor activity [1].
T61485 S07-2010
S07-2010 is a potent pan-AKR1C inhibitor, effectively inhibiting AKR1C3, AKR1C4, AKR1C1, and AKR1C2 with IC50 values of 0.19, 0.36, 0.47, and 0.73 μM, respectively. This compound induces apoptosis in A549/DDP cells and e...
T14151 AKR1C1-IN-1 NADPH
AKR1C1-IN-1 is a human 20α-hydroxysteroid dehydrogenase (AKR1C1) inhibitor (Ki: 4 nM for AKR1C1).
Cat No. Product Name Synonyms Targets
T2899 Liquiritin Liquiritigenin-4'-O-glucoside,Liquiritoside Reactive Oxygen Species
Liquiritin (Liquiritigenin-4'-O-glucoside) (LIQ) is a main component among the licorice flavonoids, and possesses anti-inflammatory and anti-cancer abilities.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-03497 AKR1C2 Protein, Human, Recombinant (His) Human E. coli
AKR1C2 is a member of the aldo/keto reductase superfamily, which consists of more than 4 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using ...
TMPJ-00207 AKR1C2 Protein, Human, Recombinant Human E. coli
Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation o...
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