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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T78702 | PTP1B/AKR1B1-IN-1 | Phosphatase | |
PTP1B/AKR1B1-IN-1 is a dual inhibitor targeting protein tyrosine phosphatase 1B (PTP1B) and aldose reductase (AKR1B1), exhibiting inhibitory potency with IC50s of 0.06 μM for PTP1B and 4.3 μM for AKR1B1. Additionally, it... | |||
T78703 | PTP1B/AKR1B1-IN-2 | Phosphatase | |
PTP1B/AKR1B1-IN-2 (Compound 7f) is a potent inhibitor targeting both PTP1B and AKR1B1 with IC50 values of 3.2 and 2.1 μM, respectively, and K i values of 4.0 and 0.9 μM. This compound acts as an insulin mimetic and enhan... | |||
T2013 | Ponalrestat | Reductase | |
Ponalrestat is an aldose reductase inhibitor. | |||
T39594 | AKR1B10-IN-1 | AKR1B10-IN-1 | |
AKR1B10-IN-1, a powerful AKR1B10 (Aldo-Keto Reductase 1B10) inhibitor, demonstrates an IC50 value of 3.5 nM. This compound effectively curtails the proliferation, metastasis, and Cisplatin (CDDP) resistance of lung cance... |