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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T60404 | NLRP3/AIM2-IN-2 | AIM2 | |
NLRP3/AIM2-IN-2 is a novel potent inhibitor with different species-specific effects on NLRP3 and AIM2 inflammasome dependent pyroptosis with IC50 of 0.2392 ± 0.0233 μ M. | |||
T60442 | NLRP3/AIM2-IN-3 | NOD , AIM2 | |
NLRP3/AIM2-IN-3 is a unique molecule that inhibits NLRP3 and AIM2 inflammasome activation in a species-specific manner. It has an IC50 value for cell lysis of 0.077 ± 0.008 μ M. NLRP3/AIM2-IN-3 is a potent inhibitor of N... | |||
T60563 | NLRP3/AIM2-IN-1 | ||
NLRP3/AIM2-IN-1 is an inhibitor of thermal sepsis (IC50 = 3.136 ± 0.7667 μM). | |||
T6887 | MCC950 sodium | CRID3 sodium salt,CP-456773,CP-456773 sodium,MCC950 | NOD-like Receptor (NLR) , NOD |
MCC950 sodium (CP-456773 sodium) is a potent and selective inhibitor of the inflammatory vesicle NLRP3 (IC50=7.5 nM in BMDMs; IC50=8.1 nM in HMDMs). MCC950 sodium has no effect on other inflammatory vesicles such as AIM2... | |||
T3701 | MCC950 | CP-456773 | NOD |
CP-456773 (MCC950 (CP-456773) and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and caspase 1 processing. MCC950 blocked canonical and... | |||
T64281 | ODN TTAGGG | ||
ODN TTAGGG (A151) is an inhibitory oligonucleotide (ODN), a TLR9, AIM2 and cGAS antagonist. oDN TTAGGG competitively inhibits AIM2 inflammasome activation by DNA and inhibits cGAS activation, exhibiting immunosuppressive... | |||
T79001 | Biotin-labeled ODN TTAGGG sodium | ||
Biotin-labeled ODN TTAGGG (sodium) is an inhibitory oligonucleotide (ODN) that functions as an antagonist to TLR9, AIM2, and cGAS. It serves as a tool for assessing cellular uptake and localization of CpG ODN using bioti... | |||
T79002 | FITC-labeled ODN TTAGGG sodium | ||
FITC-labeled ODN TTAGGG (sodium) is an inhibitory oligonucleotide that functions as an antagonist of TLR9, AIM2, and cGAS. This compound facilitates the assessment of CpG ODN cellular uptake and localization via confocal... |