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Search Results for " ache/mao-in-1 "

10

Compounds

Cat No. Product Name Synonyms Targets
T72892 AChE/MAO-IN-1
AChE/MAO-IN-1 is a potent inhibitor of human acetylcholinesterase (AChE), monoamine oxidase A (MAO-A), and monoamine oxidase B (MAO-B), demonstrating inhibitory concentrations (IC50) of 0.0248 μM, 0.0409 μM, and 0.1108 μ...
T60891 AChE/BChE/MAO-B-IN-1 MAO , AChE
AChE/BChE/MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE and MAO-B that crosses the blood-brain barrier and exhibits inhibitory effects on hAChE, hBChE and hMAO-B with IC50s of 7.31, 0.56 and 26.1...
T62172 Dual AChE-MAO B-IN-1
Dual AChE-MAO B-IN-1 (compound 15) is a safe, metabolically stable neuroprotective agent.Dual AChE-MAO B-IN-1 is a potent, orally active CNS-permeable inhibitor of human AChE (IC50=550 nM) and MAO-B (IC50=8.2 nM), and ha...
T72453 AChE/BChE/MAO-B-IN-3
AChE/BChE/MAO-B-IN-3, an indan-1-one derivative, serves as a potent inhibitor of human monoamine oxidase B (MAO-B) with an IC50 of 0.0359 μM, demonstrating significant inhibitory effects on acetylcholinesterase (AChE) an...
T74991 Dual AChE-MAO B-IN-3
Dual AChE-MAO B-IN-3 (Compound C10) is a potent inhibitor of both AChE and MAO-B, exhibiting IC50 values of 0.58 μM and 0.41 μM, respectively. This dual-binding inhibitor targets the catalytic anionic site and peripheral...
T72454 AChE/BChE/MAO-B-IN-4
AChE/BChE/MAO-B-IN-4, an indan-1-one derivative, serves as a potent inhibitor for both monoamine oxidase B (MAO-B) and acetylcholinesterase/butyrylcholinesterase (AChE/BChE) enzymes. It exhibits a strong inhibitory effec...
T78679 AChE/BuChE/MAO-B-IN-2
AChE/BuChE/MAO-B-IN-2 (compound 4b) is a potent inhibitor of AChE, BuChE, and hu MAO-B, with respective IC50 values of 5.3 μM, 12.4 μM, and 1.9±0.08 μM, indicating good in vitro blood-brain barrier (BBB) permeability. It...
T78860 MAO-B-IN-24 Monoamine Oxidase
MAO-B-IN-24 (compound 11h) is a selective, reversible, competitive inhibitor of MAO-B with an IC50 value of 1.60 μM. It also exhibits inhibitory effects on MAO-A with an IC50 of 22.42 μM. At a concentration of 10 μM, MAO...
T61049 AChE-IN-11
AChE-IN-11 (compound 5C) can be used in the Alzheimer's disease research with neuroprotective effects and good antioxidant activity (ORAC = 2.5 eq). AChE-IN-11 is a good multifunctional agent with IC 50 values of 7.9 μM...
T79299 HAChE-IN-3 Monoamine Oxidase
hAChE-IN-3 (compound 5c) serves as a potent inhibitor for AChE, BuChE, MAO-B, and BACE-1, with respective IC50 values of 0.44, 0.08, 5.15, and 0.38 μM, demonstrating its ability to cross the blood-brain barrier. This com...
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