5
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2923 | Apremilast | CC-10004 | Apoptosis , TNF , PDE |
Apremilast (CC-10004) (CC-10004) is a potent and orally active PDE4 (IC50=74 nM) with anti-inflammation activities. | |||
T21043 | Apremilast, (+/-)- | Apremilast (+/-)-, | |
Apremilast, (+/-)-, is a small molecule inhibitor of phosphodiesterase 4 (PDE4) with oral activity. It is used to treat psoriatic arthritis. | |||
T12612 | (R)-Apremilast | (R)-CC-10004 | Others |
(R)-Apremilast ((R)-CC-10004) is the enantiomer of Apremilast and one of the isoindoline derivatives. | |||
T10350 | Apremilast-d5 | Apremilast D5,CC-10004 D5 | TNF , PDE |
Apremilast D5 (CC-10004 D5) is a deuterium-labeled Apremilast. Apremilast is an orally available inhibitor of PDE-4 (IC50: 74 nM). Apremilast inhibits TNF-α release by lipopolysaccharide (IC50: 104 nM). | |||
T12656 | (Rac)-Apremilast D5 | (Rac)-CC-10004 D5 | Others |
(Rac)-Apremilast D5 is a deuterium-labeled version of the enantiomer (R)-Apremilast, also known as (R)-CC-10004, which itself is one specific form of Apremilast. |