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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T14886 | Cbz-B3A | mTOR | |
Cbz-B3A is a potent inhibitor of mTORC1 signalling, inhibits phosphorylation of eIF4E-binding protein 1 (4EBP1) and blocks translation by 68%. | |||
T60675L | AMPK activator 2 hydrochloride( 2410961-69-0 Free base) | AMPK activator 2 hydrochloride( 2410961-69-0 Free base) | AMPK |
AMPK activator 2 hydrochloride is a fluoroguanidine-containing derivative that up-regulates the AMPK signaling pathway and down-regulates mTOR/4EBP1/p70S6K.AMPK activator 2 hydrochloride inhibits the proliferation and mi... | |||
T60675 | AMPK activator 2 | AMPK | |
AMPK activator 2 is a chloroformin derivative with potential anticancer activity, which can up-regulate AMPK signaling pathway and down-regulate mTOR/4EBP1/p70S6K, and inhibit proliferation and migration of human cancer ... | |||
T74283 | RMC-4627 | ||
RMC-4627 is a selective mTORC1 inhibitor that activates 4EBP1 and inhibits tumor growth. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01769 | 4EBP1 Protein, Human, Recombinant (His) | Human | E. coli |
The translational suppressor eIF4E binding protein-1, 4E-BP1 functions as a key regulator in cellular growth, differentiation, apoptosis and survival. The Eif4ebp1 gene, encoding 4E-BP1, is a direct target of a transcrip... | |||
TMPY-06821 | THRB Protein, Human, Recombinant (His) | Human | E. coli |
Thyroid hormone receptor beta (THRB), also known as TRbeta and NR1A2, belongs to the nuclear hormone receptor family. Featuring an N-terminal transactivation domain, a central DNA-binding domain, and a hormone/ligand-bin... |
Cat No. | Product Name | ||
---|---|---|---|
L1300 | PI3K-AKT-mTOR Compound Library | 420 compounds | |
A unique collection of 420 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling; |